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Catalog Number:
03724
CAS Number:
76265-70-8
Fmoc-L-méthionine sulfoxyde
Purity:
≥ 99,5 % (HPLC chirale)
Synonym(s):
Fmoc-L-Met(O)-OH
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Informations sur le produit

Fmoc-L-methionine sulfoxide is a valuable derivative of the amino acid methionine, widely recognized for its role in peptide synthesis and research applications. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which enhances its stability and solubility, making it an ideal choice for solid-phase peptide synthesis. Researchers appreciate its utility in the synthesis of peptides with specific functionalities, particularly in the development of pharmaceuticals and biologically active compounds. The sulfoxide group not only contributes to the compound's unique properties but also allows for the introduction of oxidation states that can be crucial in various biochemical pathways.

In addition to its applications in peptide synthesis, Fmoc-L-methionine sulfoxide serves as a key building block in the design of novel therapeutics and biomolecules. Its ability to undergo selective reactions opens up possibilities for creating complex structures that are essential in drug discovery and development. This compound is particularly advantageous for researchers looking to explore the effects of methionine oxidation in biological systems, providing insights into protein function and stability. With its robust performance and versatility, Fmoc-L-methionine sulfoxide stands out as a critical tool for both academic and industrial applications.

Numéro CAS 
76265-70-8
Formule moléculaire
C 20 H 21 NON 5 S
Poids moléculaire 
387.5
Point de fusion 
165 - 170 ?C
Rotation optique 
[a] D 20 = -4 ± 2 º (C = 1 dans DMF)
Informations générales
Numéro CAS 
76265-70-8
Formule moléculaire
C 20 H 21 NON 5 S
Poids moléculaire 
387.5
Point de fusion 
165 - 170 ?C
Rotation optique 
[a] D 20 = -4 ± 2 º (C = 1 dans DMF)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-L-methionine sulfoxide is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and biologically active molecules.
  • Drug Development: Its role in medicinal chemistry is significant, as it helps in the design and optimization of peptide-based drugs, enhancing their efficacy and stability.
  • Bioconjugation: Fmoc-L-methionine sulfoxide can be used in bioconjugation processes, where it aids in attaching biomolecules to surfaces or other molecules, facilitating targeted drug delivery systems.
  • Protein Engineering: Researchers utilize this compound to modify proteins, improving their properties for various applications in biotechnology and pharmaceuticals.
  • Research in Oxidative Stress: It is valuable in studies related to oxidative stress, as it can mimic oxidative modifications in proteins, helping to understand their effects in biological systems.

Citations