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Catalog Number:
03570
CAS Number:
81144-43-6
5'- O -(4,4'-diméthoxytrityl)-2'-désoxyguanosine
Purity:
≥ 98,5 % (HPLC)
Synonym(s):
5'-DMT-2'-dG
Documents
$65.40 /250 mg
Taille
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Informations sur le produit

5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine is a versatile nucleoside derivative widely utilized in the fields of molecular biology and biochemistry. This compound serves as a crucial building block in the synthesis of oligonucleotides, enabling researchers to create custom DNA sequences for various applications, including gene therapy, diagnostics, and synthetic biology. Its unique 4,4'-dimethoxytrityl protecting group enhances stability and solubility, making it an ideal choice for automated DNA synthesis processes.

In addition to its role in oligonucleotide synthesis, 5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine is also employed in the development of novel therapeutic agents and research tools. Its ability to facilitate the incorporation of modified nucleotides into DNA strands allows for the exploration of new functionalities and improved performance in genetic applications. Researchers appreciate its compatibility with various reaction conditions, which streamlines experimental workflows and enhances overall efficiency.

Numéro CAS 
81144-43-6
Formule moléculaire
C31H31N5O6
Poids moléculaire 
569.59
Informations générales
Numéro CAS 
81144-43-6
Formule moléculaire
C31H31N5O6
Poids moléculaire 
569.59
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine is widely utilized in research focused on:

  • Nucleic Acid Synthesis: This compound serves as a crucial building block in the synthesis of oligonucleotides, which are essential for various genetic research applications, including gene editing and molecular diagnostics.
  • Pharmaceutical Development: It plays a significant role in the development of antiviral and anticancer drugs by facilitating the design of nucleotide analogs that can inhibit viral replication or cancer cell growth.
  • Biotechnology: In the field of biotechnology, it is used in the production of modified nucleic acids for therapeutic applications, enhancing the stability and efficacy of RNA-based therapies.
  • Diagnostic Tools: The compound is employed in the creation of sensitive diagnostic assays, such as PCR and qPCR, which are vital for detecting genetic material in clinical samples.
  • Research in Molecular Biology: It aids researchers in studying gene expression and regulation by providing a means to create modified nucleotides that can be incorporated into RNA transcripts for functional analysis.

Citations