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Catalog Number:
03004
CAS Number:
144701-25-7
Fmoc-β-cyclohexyl-D-alanine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-D-Cha-OH, Fmoc-3-cyclohexyl-D-alanine
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$43.87 /1G
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Informations sur le produit

Fmoc-b-cyclohexyl-D-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique cyclohexyl side chain, which enhances the hydrophobic interactions in peptides, making it particularly valuable in the design of bioactive molecules. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing stability during synthesis. Researchers often leverage this compound in the development of peptide-based therapeutics, where its structural properties can influence the pharmacokinetics and bioavailability of the resulting peptides.

Additionally, Fmoc-b-cyclohexyl-D-alanine can be employed in various applications, including the synthesis of cyclic peptides and as a building block for more complex molecular architectures. Its ability to improve solubility and stability in aqueous environments makes it an attractive choice for pharmaceutical formulations. With its unique properties and practical applications, this compound stands out as a crucial tool for researchers and industry professionals aiming to innovate in the field of medicinal chemistry.

Numéro CAS 
144701-25-7
Formule moléculaire
C 24 H 274
Poids moléculaire 
393.5
Rotation optique 
[a] D 20 = +23 ± 2º (C = 1 dans DMF)
Informations générales
Numéro CAS 
144701-25-7
Formule moléculaire
C 24 H 274
Poids moléculaire 
393.5
Rotation optique 
[a] D 20 = +23 ± 2º (C = 1 dans DMF)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-b-cyclohexyl-D-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing researchers to create complex and functional peptide sequences efficiently.
  • Drug Development: Its unique structural properties make it valuable in the design of peptide-based drugs, offering potential therapeutic applications in treating various diseases, including cancer and metabolic disorders.
  • Bioconjugation: The compound can be used in bioconjugation processes, where it helps attach peptides to other biomolecules, enhancing the specificity and efficacy of drug delivery systems.
  • Research in Neuroscience: Due to its ability to mimic natural amino acids, it is employed in studies exploring neuropeptide interactions, aiding in the understanding of neurological pathways and potential treatments for neurodegenerative diseases.
  • Material Science: Fmoc-b-cyclohexyl-D-alanine is also explored in the development of novel materials, such as hydrogels, which can be used in tissue engineering and regenerative medicine, providing scaffolds for cell growth.

Citations