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Catalog Number:
02688
CAS Number:
175453-07-3
Fmoc-3-(3'-pyridyl)-L-alanine
Purity:
≥ 99,5 % (HPLC chirale)
Synonym(s):
Fmoc-L-Ala(3'-pyridyl)-OH, Fmoc-β-(3'-pyridyl)-Ala-OH, Acide Fmoc-( S -2-amino-3-(3'-pyridyl)propanoïque
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$126.79 /1G
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Informations sur le produit

Fmoc-3-(3'-pyridyl)-L-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique pyridyl side chain enhances the compound's ability to participate in various chemical reactions, making it a valuable building block in the creation of bioactive peptides and pharmaceuticals. Researchers appreciate its stability and compatibility with standard coupling reagents, which streamlines the synthesis process and improves yield.

In practical applications, Fmoc-3-(3'-pyridyl)-L-alanine has been employed in the development of peptide-based therapeutics, particularly in targeting specific biological pathways. Its ability to form stable interactions with biological targets makes it an attractive candidate for drug design. Additionally, this compound can be used in the synthesis of peptidomimetics, which are crucial in the development of novel therapeutics. The combination of its unique structural features and practical applications positions Fmoc-3-(3'-pyridyl)-L-alanine as a key player in modern medicinal chemistry and peptide research.

Numéro CAS 
175453-07-3
Formule moléculaire
C23H20N2O4
Poids moléculaire 
388.4
Point de fusion 
150 - 170 °C
Rotation optique 
[a] D 25 = -44 ± 2,5 º (C = 1 dans DMF)
Informations générales
Numéro CAS 
175453-07-3
Formule moléculaire
C23H20N2O4
Poids moléculaire 
388.4
Point de fusion 
150 - 170 °C
Rotation optique 
[a] D 25 = -44 ± 2,5 º (C = 1 dans DMF)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-3-(3'-pyridyl)-L-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences efficiently.
  • Drug Development: Its unique structure makes it valuable in medicinal chemistry for designing novel pharmaceuticals, especially those targeting specific receptors due to its pyridine moiety.
  • Bioconjugation: The compound can be used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in developing biosensors and targeted drug delivery systems.
  • Research in Neuroscience: Due to its structural similarity to neurotransmitters, it is employed in neuroscience research to study receptor interactions and the effects of peptides on neuronal activity.
  • Protein Engineering: This chemical is instrumental in modifying proteins to enhance their stability and activity, making it a valuable tool in biotechnology and enzyme engineering.

Citations