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Catalog Number:
02589
CAS Number:
138774-94-4
Fmoc-3-(2-naphtyl)-D-alanine
Purity:
≥ 99,5 % (HPLC chirale)
Synonym(s):
Fmoc-D-Ala(2-naphtyl)-OH, Acide Fmoc-( R -2-amino-3-(naphtalén-2-yl)propanoïque
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Product Information

Fmoc-3-(2-naphthyl)-D-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during solid-phase peptide synthesis. Its unique structure, characterized by the naphthyl side chain, not only enhances the stability of peptides but also contributes to their biological activity, making it a valuable tool in medicinal chemistry and biochemistry. Researchers often leverage this compound in the design of novel peptides with improved pharmacological properties, particularly in the development of therapeutics targeting specific receptors or enzymes.

The potential applications of Fmoc-3-(2-naphthyl)-D-alanine extend to various fields, including drug discovery, materials science, and bioconjugation. Its ability to facilitate the synthesis of complex peptide structures allows for the exploration of new drug candidates and biomolecules. Additionally, the compound's favorable solubility and stability profile make it an attractive choice for researchers seeking to optimize their synthetic routes. With its proven efficacy in enhancing peptide properties, Fmoc-3-(2-naphthyl)-D-alanine stands out as a key reagent for professionals aiming to innovate in peptide-based research and development.

Synonyms
Fmoc-D-Ala(2-naphtyl)-OH, Acide Fmoc-( R -2-amino-3-(naphtalén-2-yl)propanoïque
CAS Number
138774-94-4
Purity
≥ 99,5 % (HPLC chirale)
Molecular Formula
C 28 H 234
Molecular Weight
437.5
MDL Number
MFCD00077044
PubChem ID
7130589
Melting Point
160 - 170 ?C
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = 15 ± 3 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-D-Ala(2-naphtyl)-OH, Acide Fmoc-( R -2-amino-3-(naphtalén-2-yl)propanoïque
CAS Number
138774-94-4
Purity
≥ 99,5 % (HPLC chirale)
Molecular Formula
C 28 H 234
Molecular Weight
437.5
MDL Number
MFCD00077044
PubChem ID
7130589
Melting Point
160 - 170 ?C
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = 15 ± 3 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-3-(2-naphthyl)-D-alanine is widely utilized in research focused on

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis. Its protective group allows for selective reactions, making it easier to construct complex peptide sequences.
  • Drug Development: In pharmaceutical research, it serves as a crucial component in the design of peptide-based drugs, enhancing the stability and bioactivity of therapeutic agents.
  • Bioconjugation: The compound is employed in bioconjugation techniques, where it helps attach peptides to other biomolecules, facilitating the development of targeted drug delivery systems.
  • Fluorescent Probes: Its unique structure allows for the incorporation into fluorescent probes, which are used in various imaging applications in biological research, aiding in the visualization of cellular processes.
  • Material Science: In polymer chemistry, it can be used to modify polymer properties, improving the performance of materials in applications such as drug delivery systems and smart materials.

Citations