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Catalog Number:
02585
CAS Number:
138774-93-3
Fmoc-3-(1-naphtyl)-D-alanine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-D-Ala(1-naphtyl)-OH, Acide Fmoc-( R )-2-amino-3-(naphtalén-1-yl)propanoïque
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Product Information

Fmoc-3-(1-naphthyl)-D-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the naphthyl side chain, enhances the stability and bioactivity of the resulting peptides, making it an essential building block in the design of bioactive compounds. Researchers in medicinal chemistry and biochemistry often employ this compound to create peptides with specific functionalities, such as improved binding affinity or enhanced pharmacological properties.

In addition to its role in peptide synthesis, Fmoc-3-(1-naphthyl)-D-alanine has shown potential in various applications, including the development of targeted therapeutics and the study of protein interactions. Its ability to facilitate the incorporation of non-natural amino acids into peptides allows for the exploration of novel therapeutic avenues. This compound stands out due to its favorable solubility and compatibility with standard coupling reagents, making it a preferred choice for professionals seeking reliable and efficient synthesis methods.

Synonyms
Fmoc-D-Ala(1-naphtyl)-OH, Acide Fmoc-( R )-2-amino-3-(naphtalén-1-yl)propanoïque
CAS Number
138774-93-3
Purity
≥ 98 % (HPLC)
Molecular Formula
C 28 H 234
Molecular Weight
437.5
MDL Number
MFCD00191200
PubChem ID
3462522
Melting Point
180-190 ?C
Appearance
Poudre blanche
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-D-Ala(1-naphtyl)-OH, Acide Fmoc-( R )-2-amino-3-(naphtalén-1-yl)propanoïque
CAS Number
138774-93-3
Purity
≥ 98 % (HPLC)
Molecular Formula
C 28 H 234
Molecular Weight
437.5
MDL Number
MFCD00191200
PubChem ID
3462522
Melting Point
180-190 ?C
Appearance
Poudre blanche
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-3-(1-naphthyl)-D-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others. This is crucial in developing complex peptides for pharmaceuticals.
  • Drug Development: Its unique structure makes it valuable in the design of peptide-based drugs, particularly in targeting specific receptors in the body, which can lead to more effective treatments with fewer side effects.
  • Bioconjugation: Fmoc-3-(1-naphthyl)-D-alanine is used to create bioconjugates, which are essential in the development of targeted drug delivery systems, enhancing the efficacy of therapeutic agents.
  • Research in Neuroscience: This compound is utilized in studies related to neuropeptides, contributing to the understanding of neurological functions and potential treatments for neurodegenerative diseases.
  • Material Science: Its properties are explored in the development of novel materials, such as hydrogels, which can be used in drug delivery and tissue engineering applications.

Citations