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Catalog Number:
02461
CAS Number:
35737-15-6
N α - Fmoc-L-tryptophane
Purity:
≥ 99,5 % (HPLC chirale)
Synonym(s):
Fmoc-L-Trp-OH
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Informations sur le produit

Na-Fmoc-L-tryptophan is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which allows for selective deprotection during the synthesis of peptides, making it an essential building block for researchers in the fields of biochemistry and medicinal chemistry. Its unique structure not only enhances the stability of the amino acid during synthesis but also improves the solubility of the resulting peptides, facilitating easier purification and characterization.

In practical applications, Na-Fmoc-L-tryptophan is particularly valuable in the development of pharmaceuticals targeting neurological disorders, as tryptophan is a precursor to serotonin, a key neurotransmitter. Additionally, its use in the synthesis of peptide-based therapeutics has shown promise in cancer treatment and other therapeutic areas. Researchers appreciate its reliability and efficiency in producing high-quality peptides, making it a preferred choice in laboratories focused on peptide chemistry and drug discovery.

Numéro CAS 
35737-15-6
Formule moléculaire
C26H22N2O4
Poids moléculaire 
426.5
Point de fusion 
180 - 190 °C
Rotation optique 
[a] D 20 = - 29 ± 2 ° (C = 1 dans DMF)
Informations générales
Numéro CAS 
35737-15-6
Formule moléculaire
C26H22N2O4
Poids moléculaire 
426.5
Point de fusion 
180 - 190 °C
Rotation optique 
[a] D 20 = - 29 ± 2 ° (C = 1 dans DMF)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Na-Fmoc-L-tryptophan is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex molecules with specific biological functions.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for developing new drugs, particularly those targeting neurological disorders, due to its structural similarity to neurotransmitters.
  • Bioconjugation: Na-Fmoc-L-tryptophan is used in bioconjugation processes, where it helps attach drugs or imaging agents to biomolecules, enhancing their therapeutic efficacy and targeting capabilities.
  • Protein Engineering: In the field of protein engineering, this compound aids in modifying proteins to improve their stability and functionality, which is essential for biotechnological applications.
  • Research on Tryptophan Metabolism: It is instrumental in studies investigating tryptophan metabolism and its effects on mood and behavior, providing insights into mental health research.

Citations