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Catalog Number:
02417
CAS Number:
86060-85-7
Ester pentafluorophénylique de glycine-fmoc
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-Gly-OPfp
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Product Information

Fmoc-glycine pentafluorophenyl ester is a highly versatile compound widely utilized in peptide synthesis and drug development. This compound features a unique pentafluorophenyl group, which enhances its reactivity and stability, making it an ideal choice for researchers focused on developing complex peptide structures. The Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for selective deprotection, facilitating the synthesis of peptides with high purity and yield. Its application extends to the pharmaceutical industry, where it plays a crucial role in the design of novel therapeutics, particularly in the development of peptide-based drugs.

Researchers appreciate the compound's ability to streamline the synthesis process while maintaining the integrity of sensitive functional groups. The pentafluorophenyl ester moiety not only improves solubility but also enhances the overall efficiency of coupling reactions. This makes Fmoc-glycine pentafluorophenyl ester a preferred choice for professionals aiming to optimize their peptide synthesis workflows, ensuring high-quality results in various applications, from academic research to industrial production.

Synonyms
Fmoc-Gly-OPfp
CAS Number
86060-85-7
Purity
≥ 98 % (HPLC)
Molecular Formula
C 23 H 14 F 5 NON 4
Molecular Weight
463.4
MDL Number
MFCD00037641
PubChem ID
2733282
Melting Point
155 - 160 ?C
Appearance
Poudre blanche
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-Gly-OPfp
CAS Number
86060-85-7
Purity
≥ 98 % (HPLC)
Molecular Formula
C 23 H 14 F 5 NON 4
Molecular Weight
463.4
MDL Number
MFCD00037641
PubChem ID
2733282
Melting Point
155 - 160 ?C
Appearance
Poudre blanche
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-glycine pentafluorophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing for the introduction of glycine residues with enhanced stability and reactivity.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, particularly in creating compounds with improved bioavailability.
  • Bioconjugation: The chemical is used in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other compounds, which is essential in diagnostics and therapeutic applications.
  • Research in Protein Engineering: Researchers utilize this ester in studies aimed at modifying protein structures, which can lead to advancements in enzyme activity and specificity.
  • Fluorinated Compound Research: Its pentafluorophenyl group allows for the exploration of fluorinated compounds, which can exhibit unique properties beneficial in materials science and chemical reactions.

Citations