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Catalog Number:
02400
CAS Number:
141892-41-3
Fmoc- S -4-méthoxybenzyl-L-cystéine
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-L-Cys(pMeOBzl)-OH
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Product Information

Fmoc-S-4-methoxybenzyl-L-cysteine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which facilitates the selective coupling of amino acids during solid-phase peptide synthesis. Its unique structure, incorporating a methoxybenzyl group, enhances its stability and solubility, making it an ideal choice for researchers focused on synthesizing complex peptides with improved bioactivity.

In the pharmaceutical industry, Fmoc-S-4-methoxybenzyl-L-cysteine is particularly valuable for the development of peptide-based therapeutics, including those targeting cancer and other diseases. Its ability to form disulfide bonds allows for the creation of cyclic peptides, which often exhibit enhanced potency and selectivity. Researchers appreciate its ease of use in various coupling reactions, making it a preferred choice for those aiming to streamline their synthesis processes while achieving high yields and purity.

Synonyms
Fmoc-L-Cys(pMeOBzl)-OH
CAS Number
141892-41-3
Purity
≥ 99 % (HPLC)
Molecular Formula
C 26 H 25 NON 5 S
Molecular Weight
463.6
MDL Number
MFCD00065635
Melting Point
138 - 144 ?C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = - 40 ± 2 ° (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
General Information
Synonyms
Fmoc-L-Cys(pMeOBzl)-OH
CAS Number
141892-41-3
Purity
≥ 99 % (HPLC)
Molecular Formula
C 26 H 25 NON 5 S
Molecular Weight
463.6
MDL Number
MFCD00065635
Melting Point
138 - 144 ?C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = - 40 ± 2 ° (C = 1 dans DMF)
Conditions
Conserver à 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-S-4-methoxybenzyl-L-cysteine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide structures with high purity.
  • Drug Development: Its unique properties make it valuable in the design of peptide-based drugs, especially those targeting specific receptors or enzymes, enhancing therapeutic efficacy.
  • Bioconjugation: The compound is used in bioconjugation processes, where it can be linked to other biomolecules, facilitating the development of targeted drug delivery systems.
  • Research in Cancer Therapy: It plays a role in the development of novel anticancer agents, as its modifications can improve selectivity and reduce side effects in cancer treatments.
  • Protein Engineering: The compound is instrumental in engineering proteins with enhanced stability and functionality, which is crucial for various applications in biotechnology and pharmaceuticals.

Citations