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Catalog Number:
02290
CAS Number:
98946-18-0
2,2,2-trichloroacétimidate de tert -butyle
Purity:
≥ 97 % (dosage)
Synonym(s):
TBTA
Hazmat
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Informations sur le produit

tert-Butyl 2,2,2-trichloroacetimidate is a versatile chemical compound widely utilized in organic synthesis, particularly in the preparation of various nitrogen-containing compounds. This compound serves as an effective reagent for the introduction of the trichloroacetimidate group, which is crucial in the synthesis of amides and other derivatives. Its unique structure allows for selective reactions, making it a valuable tool for researchers and professionals in the fields of medicinal chemistry and agrochemicals.

The stability and reactivity of tert-Butyl 2,2,2-trichloroacetimidate enable its application in the development of pharmaceuticals, where it can facilitate the formation of complex molecules with high precision. Additionally, its use in the synthesis of chiral intermediates highlights its importance in the production of enantiomerically pure compounds, which are essential in drug development. With its ability to streamline synthetic pathways and enhance yields, this compound stands out as a preferred choice for chemists seeking efficiency and reliability in their work.

Numéro CAS 
98946-18-0
Formule moléculaire
C6H10NOCl3
Poids moléculaire 
218.51
Point de fusion 
21 °C (lit.)
Informations générales
Numéro CAS 
98946-18-0
Formule moléculaire
C6H10NOCl3
Poids moléculaire 
218.51
Point de fusion 
21 °C (lit.)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
-
Sécurité et réglementation
Matières dangereuses
-
Antibiotique
-
Réglementé par la DEA
Non
Avertissements 
-
Applications

tert-Butyl 2,2,2-trichloroacetimidate is widely utilized in research focused on:

  • Synthesis of Amides: This compound serves as an efficient reagent for the synthesis of amides, which are essential in pharmaceuticals and agrochemicals.
  • Protecting Group in Organic Chemistry: It acts as a protecting group for amines during multi-step synthesis, allowing chemists to selectively modify other functional groups without interference.
  • Development of Peptide Synthesis: It's used in peptide synthesis, aiding in the formation of peptide bonds, which are crucial in drug development and biochemistry.
  • Research in Medicinal Chemistry: The compound is valuable in medicinal chemistry for the design and creation of new drug candidates, particularly in targeting specific biological pathways.
  • Environmental Applications: It can be utilized in the development of environmentally friendly pesticides, contributing to sustainable agricultural practices.

Citations