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Catalog Number:
01736
CAS Number:
58626-38-3
Ester N-hydroxysuccinimide de l'acide 3-maléimidobenzoïque
Purity:
≥ 99 % (HPLC)
Synonym(s):
Ester N-succinimidylique de l'acide 3-maléimidobenzoïque, N-(3-maléimidobenzoyloxy)succinimide
Documents
$86.23 /250 mg
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Product Information

3-Maleimidobenzoic acid N-hydroxysuccinimide ester is a versatile compound widely utilized in bioconjugation and protein labeling applications. This compound features a maleimide functional group, which allows for selective conjugation to thiol-containing molecules, making it an essential tool in the development of targeted therapeutics and diagnostic agents. Its ability to form stable thioether bonds with cysteine residues in proteins enhances its utility in creating stable bioconjugates, which are crucial for the development of antibody-drug conjugates (ADCs) and other biopharmaceuticals.

Researchers appreciate the compound's high reactivity and specificity, which facilitate the efficient labeling of biomolecules without compromising their biological activity. Additionally, the N-hydroxysuccinimide (NHS) ester moiety enhances the compound's solubility and stability in aqueous environments, making it suitable for various biological applications. Whether in the field of drug development, diagnostics, or proteomics, 3-Maleimidobenzoic acid N-hydroxysuccinimide ester stands out as a reliable choice for professionals seeking to advance their research and product development.

Synonyms
Ester N-succinimidylique de l'acide 3-maléimidobenzoïque, N-(3-maléimidobenzoyloxy)succinimide
CAS Number
58626-38-3
Purity
≥ 99 % (HPLC)
Molecular Formula
C15H10N2O6
Molecular Weight
314.26
MDL Number
MFCD00005514
PubChem ID
93861
Melting Point
174 - 181 ?C
Appearance
Poudre blanc cassé
Conditions
Conserver à ≤ -4 °C
General Information
Synonyms
Ester N-succinimidylique de l'acide 3-maléimidobenzoïque, N-(3-maléimidobenzoyloxy)succinimide
CAS Number
58626-38-3
Purity
≥ 99 % (HPLC)
Molecular Formula
C15H10N2O6
Molecular Weight
314.26
MDL Number
MFCD00005514
PubChem ID
93861
Melting Point
174 - 181 ?C
Appearance
Poudre blanc cassé
Conditions
Conserver à ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

3-Maleimidobenzoic acid N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Bioconjugation: This compound is commonly used to link biomolecules, such as proteins and antibodies, to other molecules, enhancing their functionality in drug delivery systems.
  • Diagnostics: It plays a crucial role in the development of diagnostic assays, allowing for the precise labeling of biomolecules, which improves the sensitivity and specificity of tests.
  • Protein Engineering: Researchers leverage this compound to modify proteins for various applications, including the creation of novel therapeutics that can better target diseases.
  • Vaccine Development: Its ability to facilitate the conjugation of antigens to carriers makes it valuable in designing more effective vaccines that elicit stronger immune responses.
  • Research in Cancer Therapy: The compound is utilized in the development of targeted cancer therapies, where it helps to attach cytotoxic agents to cancer-targeting antibodies, improving treatment efficacy.

Citations