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Catalog Number:
01543
CAS Number:
147-94-4
Cytosine 1-β-D-arabinofuranoside
Purity:
≥ 99 % (HPLC)
Synonym(s):
1-(β-D-arabinofuranosyl)cytosine, Arabinosylcytosine, Ara-C
Documents
$22.03 /1G
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Informations sur le produit

Cytosine 1-b-D-arabinofuranoside, also known as Ara-C, is a nucleoside analog that plays a crucial role in the field of molecular biology and pharmacology. This compound is primarily utilized in the treatment of certain types of cancer, particularly acute myeloid leukemia (AML) and non-Hodgkin lymphoma. Its mechanism of action involves the inhibition of DNA synthesis, making it an effective chemotherapeutic agent. Researchers and healthcare professionals appreciate Ara-C for its ability to selectively target rapidly dividing cells, which is a hallmark of cancerous tissues.

In addition to its therapeutic applications, Cytosine 1-b-D-arabinofuranoside is also employed in various research settings, particularly in studies related to nucleic acid metabolism and cellular responses to DNA damage. Its unique structural properties allow it to mimic natural nucleosides, facilitating its incorporation into RNA and DNA strands. This characteristic makes it a valuable tool for studying gene expression and the effects of nucleoside modifications. With its proven efficacy and versatile applications, Ara-C continues to be a vital compound in both clinical and research environments.

Numéro CAS 
147-94-4
Formule moléculaire
C9H13N3O5
Poids moléculaire 
243.2
Rotation optique 
[a] D 20 = +154,0 à +160,0º (C=1 dans H2O)
Informations générales
Numéro CAS 
147-94-4
Formule moléculaire
C9H13N3O5
Poids moléculaire 
243.2
Rotation optique 
[a] D 20 = +154,0 à +160,0º (C=1 dans H2O)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Cytosine 1-b-D-arabinofuranoside is widely utilized in research focused on:

  • Antiviral Research: This compound is used in the development of antiviral medications, particularly for treating viral infections like herpes simplex virus. Its ability to inhibit viral replication makes it a valuable tool for researchers.
  • Oncology: It plays a role in cancer research, specifically in the study of nucleoside analogs that can be used in chemotherapy. Its effectiveness in disrupting cancer cell proliferation is being explored in various studies.
  • Genetic Studies: Researchers utilize this compound in molecular biology to study DNA and RNA synthesis, providing insights into genetic expression and regulation. This is crucial for understanding genetic disorders and developing gene therapies.
  • Pharmaceutical Formulations: It is incorporated into drug formulations to enhance bioavailability and efficacy. Its unique structure allows for improved absorption in the body, making it a preferred choice in certain therapeutic applications.
  • Biotechnology: In the field of biotechnology, it is used in the synthesis of modified nucleotides for various applications, including the development of diagnostic tools and therapeutic agents that target specific diseases.

Citations