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Catalog Number:
01335
CAS Number:
4587-33-1
Ester de 4-nitrophényle de N α -Boc-L-asparagine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Boc-L-Asn-ONp
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Product Information

Na-Boc-L-asparagine 4-nitrophenyl ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This derivative of L-asparagine features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and reactivity, making it an ideal choice for researchers in the fields of organic chemistry and biochemistry. The presence of the 4-nitrophenyl ester moiety allows for selective activation, facilitating the coupling reactions necessary for the formation of complex peptides and proteins.

This compound is particularly valuable in the pharmaceutical industry for the development of peptide-based therapeutics and in the synthesis of bioactive molecules. Its unique properties enable chemists to achieve high yields and purity in their reactions, thus streamlining the synthesis process. Additionally, Na-Boc-L-asparagine 4-nitrophenyl ester can serve as a building block in the design of enzyme inhibitors and other biologically active compounds, showcasing its potential in drug discovery and development.

Synonyms
Boc-L-Asn-ONp
CAS Number
4587-33-1
Purity
≥ 98 % (HPLC)
Molecular Formula
C15H19N3O7
Molecular Weight
353.3
MDL Number
MFCD00056109
PubChem ID
545446
Melting Point
140-155 °C
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[α] D 20 = -38 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8°C
General Information
Synonyms
Boc-L-Asn-ONp
CAS Number
4587-33-1
Purity
≥ 98 % (HPLC)
Molecular Formula
C15H19N3O7
Molecular Weight
353.3
MDL Number
MFCD00056109
PubChem ID
545446
Melting Point
140-155 °C
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[α] D 20 = -38 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Na-Boc-L-asparagine 4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex molecules for drug development and biological studies.
  • Bioconjugation: It is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, enhancing the functionality of drugs and diagnostics.
  • Fluorescent Probes: The ester can be modified to create fluorescent probes, which are essential in imaging techniques for studying cellular processes in real-time.
  • Enzyme Inhibition Studies: Researchers utilize this compound to investigate enzyme activity and inhibition, providing insights into metabolic pathways and potential therapeutic targets.
  • Drug Delivery Systems: Its unique properties make it suitable for developing advanced drug delivery systems, improving the efficiency and specificity of therapeutic agents.

Citations