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Catalog Number:
00610
CAS Number:
81246-79-9
5'- O -(4,4'-Diméthoxytrityl)uridine
Purity:
≥ 99 % (HPLC)
Synonym(s):
DMT-Ribouridine
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Product Information

5'-O-(4,4'-dimethoxytrityl) uridine is a versatile nucleoside derivative widely utilized in the fields of molecular biology and biochemistry. This compound serves as a crucial building block in the synthesis of RNA and DNA oligonucleotides, making it invaluable for researchers engaged in genetic engineering, drug development, and therapeutic applications. Its unique 4,4'-dimethoxytrityl protecting group enhances stability and solubility, facilitating easier handling during synthesis processes.

In addition to its role in oligonucleotide synthesis, 5'-O-(4,4'-dimethoxytrityl) uridine is also employed in the development of RNA-based therapeutics, including mRNA vaccines and gene therapies. The compound's ability to protect the nucleoside from degradation while allowing for efficient incorporation into nucleic acid sequences makes it a preferred choice among professionals in the pharmaceutical and biotechnology industries. With its proven efficacy and reliability, this compound continues to support innovative research and development initiatives.

Synonyms
DMT-Ribouridine
CAS Number
81246-79-9
Purity
≥ 99 % (HPLC)
Molecular Formula
C30H30N2O8
Molecular Weight
546.6
MDL Number
MFCD00057909
PubChem ID
11092822
Appearance
Poudre blanc cassé ou jaune clair
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
DMT-Ribouridine
CAS Number
81246-79-9
Purity
≥ 99 % (HPLC)
Molecular Formula
C30H30N2O8
Molecular Weight
546.6
MDL Number
MFCD00057909
PubChem ID
11092822
Appearance
Poudre blanc cassé ou jaune clair
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

5'-O-(4,4'-dimethoxytrityl) uridine is widely utilized in research focused on:

  • Nucleic Acid Synthesis: This compound serves as a key building block in the synthesis of RNA oligonucleotides, facilitating the development of various RNA-based therapeutics and diagnostics.
  • Gene Therapy: It plays a crucial role in gene therapy applications, where modified RNA is used to deliver genetic material into cells, potentially correcting genetic disorders.
  • Antisense Oligonucleotides: The compound is instrumental in creating antisense oligonucleotides, which can inhibit gene expression and are being explored for treating diseases like cancer and viral infections.
  • Research in Molecular Biology: It is commonly used in molecular biology research to study RNA functions and interactions, helping scientists understand cellular processes and develop new biotechnological applications.
  • Pharmaceutical Development: The compound is valuable in the pharmaceutical industry for developing RNA-based drugs, offering a targeted approach to treatment with potentially fewer side effects compared to traditional small molecules.

Citations