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Catalog Number:
00133
CAS Number:
67219-55-0
5'- O -(4,4'-diméthoxytrityl)- N 4 -benzoyl-2'-désoxycytidine
Purity:
≥ 99 % (HPLC)
Synonym(s):
5'- O -DMT-NBz-2'-dC
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Product Information

5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine is a specialized nucleoside derivative that plays a crucial role in the synthesis of oligonucleotides and nucleic acid research. This compound is particularly valued for its protective groups, which enhance the stability and efficiency of DNA synthesis processes. Its unique structure allows for selective modifications, making it an essential building block in the development of therapeutic oligonucleotides, including antisense oligonucleotides and siRNA. Researchers utilize this compound to facilitate the incorporation of modified nucleotides into DNA strands, thereby improving the efficacy of gene therapies and molecular diagnostics.

In addition to its applications in genetic research, 5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine is also instrumental in the field of drug development, where it aids in the design of novel nucleoside analogs. Its ability to enhance the solubility and bioavailability of nucleic acid-based drugs makes it a valuable asset in pharmaceutical formulations. With its robust performance and versatility, this compound stands out among similar nucleoside derivatives, offering researchers and industry professionals a reliable option for advancing their work in molecular biology and therapeutic development.

Synonyms
5'- O -DMT-NBz-2'-dC
CAS Number
67219-55-0
Purity
≥ 99 % (HPLC)
Molecular Formula
C37H35N3O7
Molecular Weight
633.72
MDL Number
MFCD00010114
PubChem ID
3085359
Appearance
Poudre blanche à blanc cassé
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
5'- O -DMT-NBz-2'-dC
CAS Number
67219-55-0
Purity
≥ 99 % (HPLC)
Molecular Formula
C37H35N3O7
Molecular Weight
633.72
MDL Number
MFCD00010114
PubChem ID
3085359
Appearance
Poudre blanche à blanc cassé
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine is widely utilized in research focused on:

  • Nucleic Acid Synthesis: This compound serves as a key building block in the synthesis of oligonucleotides, which are essential for various genetic research applications, including gene therapy and molecular diagnostics.
  • Pharmaceutical Development: It is used in the development of antiviral and anticancer drugs, where modified nucleosides play a crucial role in enhancing therapeutic efficacy and reducing side effects.
  • Biotechnology: In the field of biotechnology, it aids in the design of DNA probes and primers for PCR (Polymerase Chain Reaction), facilitating accurate and efficient DNA amplification.
  • Research in Epigenetics: The compound is valuable in epigenetic studies, helping researchers understand gene regulation mechanisms through modifications in nucleic acid structures.
  • Diagnostic Tools: It is incorporated into diagnostic assays, improving the sensitivity and specificity of tests for various diseases, thereby enhancing patient outcomes.

Citations