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Catalog Number:
00131
CAS Number:
68892-41-1
5'- O -(4,4'-diméthoxytrityl)- N 2 -isobutyryl-2'-désoxyguanosine
Purity:
≥ 99 % (HPLC)
Synonym(s):
5'- O -DMT- N2 -IBu-dG, 5'- O -DMT-NiBu-dG
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Product Information

5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-deoxyguanosine is a versatile nucleoside derivative that plays a crucial role in the field of molecular biology and biochemistry. This compound is particularly valuable for researchers involved in nucleic acid synthesis and modification, as it serves as a key building block for the development of oligonucleotides and other nucleic acid-based therapeutics. Its unique structure, featuring a dimethoxytrityl protecting group, enhances its stability and solubility, making it an ideal candidate for various applications in genetic engineering and drug development.

In addition to its utility in synthetic biology, this compound is also employed in the production of modified nucleotides that can improve the efficacy and specificity of gene delivery systems. Researchers appreciate its ability to facilitate the incorporation of modified bases into oligonucleotides, which can lead to enhanced binding affinity and resistance to nucleases. With its broad range of applications, 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-deoxyguanosine is an essential tool for advancing research in genomics, therapeutics, and molecular diagnostics.

Synonyms
5'- O -DMT- N2 -IBu-dG, 5'- O -DMT-NiBu-dG
CAS Number
68892-41-1
Purity
≥ 99 % (HPLC)
Molecular Formula
C35H37N5O7
Molecular Weight
639.72
MDL Number
MFCD00010059
PubChem ID
135444049
Appearance
Poudre blanche à blanc cassé
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
5'- O -DMT- N2 -IBu-dG, 5'- O -DMT-NiBu-dG
CAS Number
68892-41-1
Purity
≥ 99 % (HPLC)
Molecular Formula
C35H37N5O7
Molecular Weight
639.72
MDL Number
MFCD00010059
PubChem ID
135444049
Appearance
Poudre blanche à blanc cassé
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-deoxyguanosine is widely utilized in research focused on:

  • Nucleic Acid Synthesis: This compound serves as a key building block in the synthesis of oligonucleotides, which are essential for various genetic research applications, including gene editing and PCR.
  • Drug Development: It plays a significant role in the development of antiviral and anticancer drugs by acting as a nucleotide analog, helping researchers to design more effective therapeutic agents.
  • Biotechnology: The compound is used in the production of modified nucleotides for RNA interference (RNAi) studies, aiding in the exploration of gene function and regulation.
  • Diagnostic Tools: It is employed in the creation of diagnostic assays, enhancing the sensitivity and specificity of tests for various diseases by improving the stability and performance of nucleic acid probes.
  • Research on Cellular Mechanisms: This chemical is instrumental in studying cellular processes such as replication and transcription, providing insights that are crucial for understanding cellular behavior and disease mechanisms.

Citations