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Catalog Number:
38094
CAS Number:
54527-84-3
Chlorhydrate de nicardipine
Grade:
USP
Purity:
98 - 102 % (dosage, sur une base sèche)
Synonym(s):
Chlorhydrate de méthyl 2-[méthyl(phénylméthyl)amino]éthyl ester d'acide 1,4-dihydro-2,6-diméthyl-4-(3-nitrophényl)-3,5-pyridinedicarboxylique
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$131.90 /5G
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Informations sur le produit

Nicardipine hydrochloride is a potent calcium channel blocker primarily utilized in the management of hypertension and angina pectoris. This compound works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure. Its unique structure allows for effective targeting of L-type calcium channels, making it a preferred choice in clinical settings for patients requiring precise blood pressure control.

In addition to its cardiovascular applications, Nicardipine hydrochloride has shown promise in various research contexts, including studies on cerebral vasospasm and as a potential therapeutic agent in neuroprotection. Its ability to cross the blood-brain barrier opens avenues for further exploration in treating neurological conditions. With a favorable pharmacokinetic profile, including rapid absorption and a relatively short half-life, this compound is ideal for both acute and chronic management of cardiovascular conditions. Researchers and healthcare professionals can rely on Nicardipine hydrochloride for its efficacy and versatility in therapeutic applications.

Numéro CAS 
54527-84-3
Formule moléculaire
C26H29N3O6 · HCl
Poids moléculaire 
515.99
Informations générales
Numéro CAS 
54527-84-3
Formule moléculaire
C26H29N3O6 · HCl
Poids moléculaire 
515.99
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Nicardipine hydrochloride is widely utilized in research focused on:

  • Cardiovascular Medicine: This compound is primarily used as a medication to treat high blood pressure and angina. It works by relaxing blood vessels, which improves blood flow and reduces the heart's workload.
  • Hypertensive Emergencies: In acute medical settings, nicardipine is administered intravenously to manage severe hypertension, providing rapid control of blood pressure in critical situations.
  • Research on Calcium Channel Blockers: Researchers study nicardipine to understand its effects on calcium channels, which can lead to the development of new cardiovascular therapies and improved treatment protocols.
  • Pharmaceutical Formulations: The compound is also explored in the formulation of sustained-release medications, enhancing patient compliance by reducing the frequency of dosing.
  • Comparative Studies: Nicardipine is often compared with other antihypertensive agents in clinical trials, providing insights into its efficacy and safety profile, which can guide treatment choices in various patient populations.

Citations