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Catalog Number:
37883
CAS Number:
72509-76-3
Félodipine
Grade:
USP
Purity:
98 - 101 % (dosage, sur une base sèche)
Synonym(s):
Acide 4-(2,3-dichlorophényl)-1,4-dihydro-2,6-diméthyl-3,5-pyridinedicarboxylique Ester éthylique et méthylique, 4-(2,3-dichlorophényl)-1,4-dihydro-2,6-diméthyl-3,5-pyridinedicarboxylate d'éthyle et de méthyle
Hazmat
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$18.53 /1G
Taille
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Informations sur le produit

Felodipine is a potent calcium channel blocker primarily used in the management of hypertension and angina. This dihydropyridine derivative works by inhibiting calcium influx into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure. Its unique structure, featuring a dichlorophenyl group, enhances its selectivity and efficacy, making it a preferred choice in clinical settings. Felodipine is often formulated in extended-release preparations, allowing for once-daily dosing, which improves patient compliance and therapeutic outcomes.

In addition to its cardiovascular applications, Felodipine is also being explored for its potential benefits in treating other conditions, such as Raynaud's phenomenon and certain types of heart failure. Researchers appreciate its favorable pharmacokinetic profile, which includes a long half-life and minimal side effects compared to other antihypertensives. This compound's ability to provide sustained blood pressure control while minimizing adverse reactions positions it as a valuable option for healthcare professionals seeking effective treatment strategies.

Numéro CAS 
72509-76-3
Formule moléculaire
C 18 H 19 Cl 2 NO 4
Poids moléculaire 
384.25
Point de fusion 
142 - 146 ?C
Informations générales
Numéro CAS 
72509-76-3
Formule moléculaire
C 18 H 19 Cl 2 NO 4
Poids moléculaire 
384.25
Point de fusion 
142 - 146 ?C
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Felodipine is widely utilized in research focused on:

  • Cardiovascular Health: Primarily used as an antihypertensive agent, it helps manage high blood pressure, reducing the risk of heart-related complications.
  • Pharmaceutical Development: Employed in the formulation of various medications, it serves as a model compound for studying drug absorption and metabolism.
  • Clinical Trials: Frequently involved in clinical studies aimed at evaluating the efficacy of new treatments for hypertension and related cardiovascular conditions.
  • Research on Drug Interactions: Useful in studies assessing how different substances interact with antihypertensive medications, aiding in safer prescribing practices.
  • Patient Compliance Studies: Investigated for its role in improving patient adherence to treatment regimens due to its extended-release formulations, which require less frequent dosing.

Citations