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Catalog Number:
38240
CAS Number:
112887-68-0
Raltitrexed
Purity:
≥ 98 % (HPLC)
Synonym(s):
Acide N -[[5-[[(1,4-dihydro-2-méthyl-4-oxo-6-quinazolinyl)méthyl]méthylamino]-2-thiényl]carbonyl]-L-glutamique, ICI-D-1694
Hazmat
Documents
$334.10 /50 mg
Taille
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Informations sur le produit
Numéro CAS 
112887-68-0
Formule moléculaire
C21H22N4O6S
Poids moléculaire 
0
Point de fusion 
176 °C (déc.)
Rotation optique 
[a] D 20 = -15 à -20 ° (C=1 dans MeOH)
Informations générales
Numéro CAS 
112887-68-0
Formule moléculaire
C21H22N4O6S
Poids moléculaire 
0
Point de fusion 
176 °C (déc.)
Rotation optique 
[a] D 20 = -15 à -20 ° (C=1 dans MeOH)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Raltitrexed is widely utilized in research focused on

  • Cancer Treatment: This compound is primarily used as an anti-cancer agent, particularly in the treatment of colorectal cancer. It acts as a thymidylate synthase inhibitor, disrupting DNA synthesis in rapidly dividing cancer cells.
  • Pharmaceutical Development: Raltitrexed serves as a critical reference compound in the development of new anti-cancer drugs. Researchers study its mechanisms to design more effective therapies with fewer side effects.
  • Combination Therapies: It is often used in combination with other chemotherapeutic agents to enhance treatment efficacy. This synergistic approach can improve patient outcomes in various cancer types.
  • Clinical Trials: Raltitrexed is frequently involved in clinical trials aimed at evaluating new treatment regimens. Its established profile helps researchers assess the effectiveness of novel therapeutic strategies.
  • Research on Drug Resistance: Scientists study Raltitrexed to understand mechanisms of drug resistance in cancer cells. Insights gained can lead to the development of strategies to overcome resistance and improve treatment success.

Citations