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Catalog Number:
32499
CAS Number:
27848-84-6
Nicergoline
Purity:
≥ 98 % (HPLC, T)
Synonym(s):
Ester méthylique 10-méthoxy-1,6-diméthylergoline-8-de l'acide 5-bromonicotinique, [(8 R ,10 S )-10-méthoxy-1,6-diméthylergolin-8-yl]méthyl5-bromopyridine-3-carboxylate
Documents
$65.40 /250 mg
Taille
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Product Information

La nicergoline est un dérivé de l'ergot de seigle et un vasodilatateur qui augmente le flux sanguin dans le cerveau ! Conserver à l'abri des agents oxydants.

Synonyms
Ester méthylique 10-méthoxy-1,6-diméthylergoline-8-de l'acide 5-bromonicotinique, [(8 R ,10 S )-10-méthoxy-1,6-diméthylergolin-8-yl]méthyl5-bromopyridine-3-carboxylate
CAS Number
27848-84-6
Purity
≥ 98 % (HPLC, T)
Molecular Formula
C24H26BrN3O3
Molecular Weight
484.39
MDL Number
MFCD00869626
PubChem ID
4475
Melting Point
134 - 138 °C
Appearance
Poudre blanche ou jaunâtre
Optical Rotation
[a]20/D= +5,2 à +6,2° (C=5 dans EtOH(95vol%))
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
Ester méthylique 10-méthoxy-1,6-diméthylergoline-8-de l'acide 5-bromonicotinique, [(8 R ,10 S )-10-méthoxy-1,6-diméthylergolin-8-yl]méthyl5-bromopyridine-3-carboxylate
CAS Number
27848-84-6
Purity
≥ 98 % (HPLC, T)
Molecular Formula
C24H26BrN3O3
Molecular Weight
484.39
MDL Number
MFCD00869626
PubChem ID
4475
Melting Point
134 - 138 °C
Appearance
Poudre blanche ou jaunâtre
Optical Rotation
[a]20/D= +5,2 à +6,2° (C=5 dans EtOH(95vol%))
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Nicergoline is widely utilized in research focused on:

  • Cognitive Enhancement: This compound is often studied for its potential to improve cognitive function, particularly in elderly patients suffering from cognitive decline. Researchers explore its effects on memory and attention, making it relevant in geriatric medicine.
  • Vascular Health: Nicergoline is known for its vasodilatory properties, which help improve blood flow. This application is beneficial in treating conditions like peripheral vascular disease, where enhanced circulation can alleviate symptoms.
  • Neuroprotective Effects: Studies indicate that Nicergoline may protect neurons from damage, making it a subject of interest in neurodegenerative disease research, such as Alzheimer's and Parkinson's disease.
  • Ophthalmology: The compound is explored for its potential benefits in treating age-related macular degeneration (AMD) by improving retinal blood flow, which is crucial for maintaining vision in older adults.
  • Pharmaceutical Formulations: Nicergoline is often included in various formulations aimed at enhancing cognitive function and improving quality of life in patients with vascular-related cognitive impairment, showcasing its versatility in the pharmaceutical industry.

Citations