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Catalog Number:
00128
CAS Number:
24424-99-5
Di-tert-butyl pyrocarbonate
Purity:
≥ 99% (GC)
Synonym(s):
Boc anhydride, Di-tert-butyl dicarbonate, Pyrocarbonic acid di-tert-butyl ester
Hazmat
Documents
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Product Information

Di-tert-butyl pyrocarbonate is a versatile chemical compound widely utilized in organic synthesis and as a protecting group for amines and alcohols. This compound is particularly valued for its ability to selectively protect functional groups, allowing for more complex synthetic pathways in the development of pharmaceuticals and fine chemicals. Its stability and ease of use make it an ideal choice for researchers looking to streamline their synthetic processes.

In addition to its role in organic synthesis, Di-tert-butyl pyrocarbonate is also employed in the preparation of various derivatives, enhancing the efficiency of chemical reactions. Its unique properties allow for high yields and purity in the final products, making it a preferred choice in laboratories and industrial applications. Researchers and professionals in the chemical industry can benefit from its application in the synthesis of complex molecules, thereby facilitating advancements in drug development and materials science.

Synonyms
Boc anhydride, Di-tert-butyl dicarbonate, Pyrocarbonic acid di-tert-butyl ester
CAS Number
24424-99-5
Purity
≥ 99% (GC)
Molecular Formula
C10H18O5
Molecular Weight
218.25
MDL Number
MFCD00008805
PubChem ID
90495
Melting Point
20 - 25 °C
Density
0.95
Appearance
Colorless liquid or white crystal
Boiling Point
56-57°C/0.5mmHg
Refractive Index
1.409
Conditions
Store at 0-8 °C
Warnings
Danger
General Information
Synonyms
Boc anhydride, Di-tert-butyl dicarbonate, Pyrocarbonic acid di-tert-butyl ester
CAS Number
24424-99-5
Purity
≥ 99% (GC)
Molecular Formula
C10H18O5
Molecular Weight
218.25
MDL Number
MFCD00008805
PubChem ID
90495
Melting Point
20 - 25 °C
Density
0.95
Appearance
Colorless liquid or white crystal
Boiling Point
56-57°C/0.5mmHg
Refractive Index
1.409
Conditions
Store at 0-8 °C
Warnings
Danger
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
Danger
Applications

Di-tert-butyl pyrocarbonate is widely utilized in research focused on:

  • Protecting Groups in Organic Synthesis: This compound serves as an effective protecting group for amines and alcohols, allowing chemists to selectively modify other functional groups without interference.
  • Pharmaceutical Development: It plays a crucial role in the synthesis of pharmaceutical intermediates, enhancing the efficiency of drug development processes by providing better yields and purities.
  • Polymer Chemistry: Used in the production of polymers, it helps in the modification of polymer properties, leading to materials with enhanced thermal and mechanical stability.
  • Bioconjugation Techniques: In biochemistry, it is employed in bioconjugation methods, facilitating the attachment of biomolecules to surfaces or other molecules, which is vital for developing biosensors and drug delivery systems.
  • Analytical Chemistry: This compound is also utilized in analytical methods, such as chromatography, where it aids in the derivatization of analytes, improving detection sensitivity and specificity.

Citations