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Catalog Number:
00110
CAS Number:
693-13-0
N,N'-Diisopropylcarbodiimide
Purity:
≥ 99% (Assay)
Synonym(s):
DIC
Hazmat
Documents
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Product Information

N,N'-Diisopropylcarbodiimide is a versatile coupling agent widely utilized in organic synthesis, particularly in the formation of amide bonds. This compound is recognized for its efficiency in facilitating peptide synthesis and other coupling reactions, making it an essential tool for researchers in the fields of biochemistry and pharmaceuticals. Its unique structure allows for a high degree of reactivity, which can significantly enhance the yield of desired products while minimizing side reactions.

In addition to its role in peptide synthesis, N,N'-Diisopropylcarbodiimide is also employed in the preparation of various esters and in the activation of carboxylic acids for subsequent reactions. Its ability to operate under mild conditions makes it suitable for sensitive substrates, thus expanding its applicability in diverse chemical processes. Researchers and industry professionals appreciate its reliability and effectiveness, particularly when compared to other coupling agents, as it often leads to cleaner reaction profiles and higher product purity.

Synonyms
DIC
CAS Number
693-13-0
Purity
≥ 99% (Assay)
Molecular Formula
C7H14N2
Molecular Weight
126.2
MDL Number
MFCD00065689
PubChem ID
12734
Density
0.810 - 0.814 g/mL
Appearance
Colorless to white transparent liquid
Boiling Point
145 - 148 °C
Refractive Index
n20/D 1.42 - 1.44
Conditions
Store at RT
Warnings
Danger
General Information
Synonyms
DIC
CAS Number
693-13-0
Purity
≥ 99% (Assay)
Molecular Formula
C7H14N2
Molecular Weight
126.2
MDL Number
MFCD00065689
PubChem ID
12734
Density
0.810 - 0.814 g/mL
Appearance
Colorless to white transparent liquid
Boiling Point
145 - 148 °C
Refractive Index
n20/D 1.42 - 1.44
Conditions
Store at RT
Warnings
Danger
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
Danger
Applications

N,N'-Diisopropylcarbodiimide is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a coupling agent in the formation of peptide bonds, making it essential for synthesizing peptides in pharmaceutical research.
  • Carboxylic Acid Activation: It effectively activates carboxylic acids for subsequent reactions, streamlining processes in organic synthesis and enhancing yield.
  • Bioconjugation: Used in bioconjugation techniques, it facilitates the attachment of biomolecules, which is crucial in developing targeted drug delivery systems.
  • Polymer Chemistry: It plays a significant role in creating polyurethanes and other polymers, contributing to advancements in materials science.
  • Cross-Linking Agents: This compound is employed as a cross-linking agent in various applications, improving the mechanical properties of materials in industries such as coatings and adhesives.

Citations