This compound is used to incorporate serine into peptides, with the Fmoc group protecting the amino side. Serine is important for creating phosphorylation sites within peptides, mimicking protein segments involved in signal transduction, protein-protein interactions, and enzyme catalysis. Fmoc-L-Serine is thus critical in the synthesis of peptides for studies on phosphorylation-dependent signaling pathways and for the creation of peptide-based probes and therapeutics.