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Catalog Number:
00632
CAS Number:
329-98-6
Phenylmethylsulfonyl fluoride
Purity:
99 - 100% (GC)
Synonym(s):
α-Toluenesulfonyl fluoride, Benzenemethanesulfonyl fluoride, Benzylsulfonyl fluoride
Hazmat
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Product Information

Used as a Protease inhibitor such as Chymotrypsin, Trypsin and Thrombin as well as Acetylcholineesterase.

Synonyms
α-Toluenesulfonyl fluoride, Benzenemethanesulfonyl fluoride, Benzylsulfonyl fluoride
CAS Number
329-98-6
Purity
99 - 100% (GC)
Molecular Formula
C7H7FO2S
Molecular Weight
0
MDL Number
MFCD00007424
PubChem ID
4784
Melting Point
92 - 95 °C
Appearance
White crystalline solid
Conditions
Store at 0 - 8 °C
General Information
Synonyms
α-Toluenesulfonyl fluoride, Benzenemethanesulfonyl fluoride, Benzylsulfonyl fluoride
CAS Number
329-98-6
Purity
99 - 100% (GC)
Molecular Formula
C7H7FO2S
Molecular Weight
0
MDL Number
MFCD00007424
PubChem ID
4784
Melting Point
92 - 95 °C
Appearance
White crystalline solid
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Phenylmethylsulfonyl fluoride is widely utilized in research focused on:

  • Protein Modification: This compound is commonly used as a reagent to selectively modify proteins, particularly in studies involving enzyme inhibition. It helps researchers understand enzyme mechanisms and develop potential inhibitors.
  • Drug Development: In pharmaceutical research, it serves as a valuable tool for synthesizing sulfonamide compounds, which are essential in creating new drugs with improved efficacy and reduced side effects.
  • Biochemical Assays: It is employed in various biochemical assays to study the activity of serine proteases, aiding in the identification of potential therapeutic targets in diseases like cancer and inflammation.
  • Material Science: The compound is used in the development of specialty polymers and coatings, enhancing material properties such as chemical resistance and durability, which are crucial in industrial applications.
  • Environmental Analysis: It plays a role in environmental chemistry, particularly in the detection and analysis of sulfonyl fluoride compounds in various matrices, contributing to pollution monitoring and regulatory compliance.

Citations