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Catalog Number:
33021
CAS Number:
310427-94-2
Arg-Glu(EDANS)-(Asn670,Leu671-Amyloid β/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt
Synonym(s):
H-Arg-Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(DABCYL)-Arg-OHtrifluoroacetate salt
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$428.34 /1MG
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Product Information

Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoro is a specialized peptide that plays a crucial role in biomedical research, particularly in the study of Alzheimer's disease and related neurodegenerative disorders. This compound is designed for use in fluorescence resonance energy transfer (FRET) applications, where it serves as a donor-acceptor pair due to its unique EDANS and DABCYL moieties. Researchers utilize this peptide to investigate protein interactions and conformational changes, providing insights into amyloid-beta aggregation and its implications in Alzheimer's pathology.

The compound's specific sequence and modifications enhance its stability and effectiveness in various assays, making it a valuable tool for scientists exploring therapeutic targets and mechanisms of action in neurodegeneration. Its ability to facilitate real-time monitoring of molecular interactions positions it as a preferred choice for researchers aiming to develop innovative diagnostic and therapeutic strategies. With its unique properties, this peptide stands out in the field of peptide-based research, offering significant advantages over traditional methods.

Synonyms
H-Arg-Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(DABCYL)-Arg-OHtrifluoroacetate salt
CAS Number
310427-94-2
Molecular Formula
C91H129N25O25S·C2HF3O2
Molecular Weight
2119.27
MDL Number
MFCD18782560
Conditions
Store at ≤ -10 °C
General Information
Synonyms
H-Arg-Glu(EDANS)-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(DABCYL)-Arg-OHtrifluoroacetate salt
CAS Number
310427-94-2
Molecular Formula
C91H129N25O25S·C2HF3O2
Molecular Weight
2119.27
MDL Number
MFCD18782560
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoro is widely utilized in research focused on:

  • Alzheimer's Disease Research: This compound is instrumental in studying amyloid-beta peptides, which are crucial in understanding the pathology of Alzheimer's disease. Researchers use it to develop potential therapeutic strategies.
  • Biomarker Development: It aids in the identification of biomarkers for neurodegenerative diseases, helping in early diagnosis and monitoring of disease progression.
  • Drug Discovery: The compound serves as a valuable tool in screening for new drugs that can inhibit amyloid-beta aggregation, providing a pathway for innovative treatments.
  • Fluorescent Labeling: Its properties allow for effective fluorescent labeling in assays, enhancing the visualization of protein interactions and dynamics in cellular environments.
  • Peptide Synthesis: This chemical is used in synthesizing peptides for various applications in research, offering a reliable method for producing high-purity compounds for experimental use.