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Catalog Number:
02372
CAS Number:
79990-15-1
Fmoc-D-alanine
Purity:
≥ 99.5% (HPLC, Chiral purity)
Synonym(s):
Fmoc-D-Ala-OH
Documents
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Product Information

Fmoc-D-alanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which allows for selective deprotection during the synthesis of peptides, making it an essential building block for researchers in the fields of biochemistry and medicinal chemistry. Its unique structure not only enhances stability but also facilitates the formation of complex peptide chains, crucial for developing therapeutic agents and studying protein interactions.

In addition to its role in peptide synthesis, Fmoc-D-alanine is also employed in various applications, including the production of pharmaceuticals, agrochemicals, and specialty chemicals. Its compatibility with automated synthesizers streamlines the process of peptide assembly, making it a preferred choice among professionals seeking efficiency and reliability. With its proven track record in enhancing peptide synthesis and its broad applicability across multiple industries, Fmoc-D-alanine stands out as a key compound for researchers and manufacturers alike.

Synonyms
Fmoc-D-Ala-OH
CAS Number
79990-15-1
Purity
≥ 99.5% (HPLC, Chiral purity)
Molecular Formula
C18H17NO4
Molecular Weight
311.3
MDL Number
MFCD00062960
PubChem ID
100108
Melting Point
147-157 °C
Appearance
White powder
Optical Rotation
[a]D20 = +18 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Ala-OH
CAS Number
79990-15-1
Purity
≥ 99.5% (HPLC, Chiral purity)
Molecular Formula
C18H17NO4
Molecular Weight
311.3
MDL Number
MFCD00062960
PubChem ID
100108
Melting Point
147-157 °C
Appearance
White powder
Optical Rotation
[a]D20 = +18 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs, enhancing their stability and bioavailability, which is crucial for effective therapeutic outcomes.
  • Biotechnology: Fmoc-D-alanine is employed in the production of recombinant proteins, aiding in the development of biologics and therapeutic proteins that are vital in treating various diseases.
  • Analytical Chemistry: This compound is useful in chromatographic techniques for the separation and analysis of amino acids and peptides, providing accurate results for quality control in laboratories.
  • Material Science: It is also explored in the development of new materials, particularly in creating hydrogels and other polymers that can be used in drug delivery systems.

Citations