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Catalog Number:
01417
CAS Number:
108321-42-2
Geneticin disulfate salt
Purity:
Potency ≥ 700 ug/mg (anhydrous basis)
Synonym(s):
Antibiotic G418, G 418 disulfate salt, Aminoglycoside antibiotic
Antibiotic
Documents
$40.00 /1G
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Product Information

Geneticin disulfate salt, a potent aminoglycoside antibiotic, is widely recognized for its ability to inhibit protein synthesis in prokaryotic cells, making it an essential tool in molecular biology and genetic research. This compound is particularly valuable in the selection of genetically modified cells, as it effectively eliminates non-resistant cells, thereby ensuring the growth of only those that have successfully integrated the desired genetic material. Researchers utilize Geneticin disulfate salt in various applications, including the establishment of stable cell lines and the development of transgenic organisms. Its high efficacy and specificity make it a preferred choice for scientists aiming to conduct precise genetic manipulations.

In addition to its applications in research, Geneticin disulfate salt is also utilized in the pharmaceutical industry for the production of antibiotic formulations. Its unique properties allow for effective treatment options against certain bacterial infections, showcasing its versatility beyond laboratory settings. With its proven track record in enhancing genetic studies and its potential in therapeutic applications, Geneticin disulfate salt remains a critical asset for researchers and industry professionals alike.

Synonyms
Antibiotic G418, G 418 disulfate salt, Aminoglycoside antibiotic
CAS Number
108321-42-2
Purity
Potency ≥ 700 ug/mg (anhydrous basis)
Molecular Formula
C20H40N4O10·2H2SO4
Molecular Weight
692.7
MDL Number
MFCD05664725
PubChem ID
354577
Appearance
White powder
Optical Rotation
[a]D20 = 104 - 121 ° (Lit.)
Conditions
Store at 0 - 8 °C
Potency
≥ 700 mg/mg (anhydrous)
General Information
Synonyms
Antibiotic G418, G 418 disulfate salt, Aminoglycoside antibiotic
CAS Number
108321-42-2
Purity
Potency ≥ 700 ug/mg (anhydrous basis)
Molecular Formula
C20H40N4O10·2H2SO4
Molecular Weight
692.7
MDL Number
MFCD05664725
PubChem ID
354577
Appearance
White powder
Optical Rotation
[a]D20 = 104 - 121 ° (Lit.)
Conditions
Store at 0 - 8 °C
Potency
≥ 700 mg/mg (anhydrous)
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Geneticin disulfate salt is widely utilized in research focused on:

  • Cell Culture: This compound is commonly used as a selective antibiotic in cell culture systems, particularly for the selection of genetically modified cells that express resistance genes. This is crucial for researchers developing transgenic models.
  • Gene Therapy: In gene therapy applications, it helps in the selection of successfully transfected cells, ensuring that only those with the desired genetic modifications are propagated. This enhances the efficiency of therapeutic approaches.
  • Pharmaceutical Development: It plays a role in the development of new drugs by providing a means to study the effects of gene modifications on drug responses, thereby aiding in personalized medicine initiatives.
  • Biotechnology Research: Geneticin disulfate salt is essential in the biotechnology sector for creating stable cell lines that produce recombinant proteins, which are vital for vaccine production and therapeutic proteins.
  • Functional Genomics: Researchers utilize this compound in functional genomics studies to investigate gene function and interaction, allowing for a deeper understanding of cellular processes and disease mechanisms.

Citations