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Catalog Number:
03769
CAS Number:
200354-34-3
Fmoc-S-ethyl-L-cysteine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Cys(Et)-OH
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Product Information

Fmoc-S-ethyl-L-cysteine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued in the field of medicinal chemistry for its ability to introduce a thiol group into peptides, which can enhance their biological activity and stability. The Fmoc (9-fluorenylmethyloxycarbonyl) protecting group allows for selective deprotection, making it an ideal choice for solid-phase peptide synthesis. Researchers utilize Fmoc-S-ethyl-L-cysteine to create peptides with enhanced pharmacological properties, such as improved binding affinity and specificity for target proteins. Its unique structure not only facilitates the incorporation of sulfur into peptide chains but also provides a robust platform for the development of novel therapeutics.

In addition to its applications in peptide synthesis, Fmoc-S-ethyl-L-cysteine is also explored for its potential in the development of bioconjugates and targeted drug delivery systems. The compound's ability to form disulfide bonds can be leveraged to create stable linkages in drug formulations, enhancing their efficacy and reducing side effects. With its growing importance in pharmaceutical research and development, Fmoc-S-ethyl-L-cysteine stands out as a valuable tool for scientists aiming to innovate in the field of drug design and delivery.

Synonyms
Fmoc-L-Cys(Et)-OH
CAS Number
200354-34-3
Purity
≥ 99% (HPLC)
Molecular Formula
C20H21NO4S
Molecular Weight
371.5
MDL Number
MFCD00151921
PubChem ID
74765068
Melting Point
130.5 - 132.5 ?C
Appearance
White powder
Optical Rotation
[a]20D = -12 to -13 ° (C=1 in MeOH)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-Cys(Et)-OH
CAS Number
200354-34-3
Purity
≥ 99% (HPLC)
Molecular Formula
C20H21NO4S
Molecular Weight
371.5
MDL Number
MFCD00151921
PubChem ID
74765068
Melting Point
130.5 - 132.5 ?C
Appearance
White powder
Optical Rotation
[a]20D = -12 to -13 ° (C=1 in MeOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-S-ethyl-L-cysteine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of sulfur-containing amino acids which can enhance the properties of the resulting peptides.
  • Drug Development: Researchers leverage Fmoc-S-ethyl-L-cysteine in the design of novel pharmaceuticals, especially those targeting specific biological pathways, due to its unique structural features that can improve bioactivity.
  • Bioconjugation: The compound is used in bioconjugation processes, enabling the attachment of biomolecules to drugs or imaging agents, which can enhance the specificity and efficacy of therapeutic applications.
  • Protein Engineering: It plays a significant role in protein engineering, where it can be incorporated into proteins to study their function or to create proteins with enhanced stability and activity.
  • Research in Redox Biology: Fmoc-S-ethyl-L-cysteine is valuable in studies related to redox biology, helping researchers explore the role of thiol groups in cellular processes and oxidative stress responses.

Citations