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Catalog Number:
35142
CAS Number:
1416561-90-4
O-Propargyl-puromycine (OPP)
Purity:
≥ 95% (HPLC)
Documents
$634.00 /5MG
Pack Size Availability Price
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Product Information

O-Propargyl-puromycine (OPP) is a potent chemical compound recognized for its unique ability to selectively inhibit protein synthesis, making it an invaluable tool in biochemical research and drug development. This compound is particularly notable for its application in studying cellular processes and understanding the mechanisms of action in various diseases, including cancer. OPP's structure, featuring a propargyl group, enhances its reactivity and allows for specific interactions with ribosomal components, thereby providing researchers with a powerful means to dissect the intricacies of translation and protein function.

In practical applications, OPP has been utilized in the development of novel therapeutic strategies, particularly in targeting resistant cancer cells. Its ability to induce apoptosis in specific cell lines highlights its potential as a lead compound in anti-cancer drug discovery. Additionally, OPP's unique properties make it suitable for use in various biochemical assays, enabling scientists to explore new avenues in molecular biology and pharmacology. With its targeted action and versatility, OPP stands out as a critical resource for researchers aiming to innovate in the fields of drug development and cellular biology.

CAS Number
1416561-90-4
Purity
≥ 95% (HPLC)
Molecular Formula
C24H29N7O5
Molecular Weight
495.54
PubChem ID
78118440
Appearance
Off-white to slightly grey crystalline
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
General Information
CAS Number
1416561-90-4
Purity
≥ 95% (HPLC)
Molecular Formula
C24H29N7O5
Molecular Weight
495.54
PubChem ID
78118440
Appearance
Off-white to slightly grey crystalline
Conditions
Store at -10 °C, desiccate and shipped at ambient temperature
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

O-Propargyl-puromycine (OPP) is widely utilized in research focused on:

  • Cell Biology: OPP is used as a powerful tool for studying protein synthesis in living cells. By incorporating OPP into cellular systems, researchers can track newly synthesized proteins, providing insights into cellular functions and mechanisms.
  • Neuroscience: In neuroscience research, OPP helps in understanding neuronal activity and synaptic functions. Its ability to label newly formed proteins allows scientists to investigate processes like memory formation and synaptic plasticity.
  • Drug Development: OPP is valuable in the pharmaceutical industry for screening potential drug candidates. Its unique properties enable researchers to evaluate how new compounds affect protein synthesis, aiding in the identification of effective therapeutic agents.
  • Biotechnology: This compound is utilized in biotechnological applications, particularly in the development of biosensors. OPP can be used to create assays that detect specific proteins, which is crucial for diagnostics and monitoring biological processes.
  • Cancer Research: OPP plays a significant role in cancer studies by helping to elucidate the mechanisms of tumor growth and metastasis. Its application in tracking protein synthesis can reveal how cancer cells adapt and proliferate, leading to potential therapeutic targets.