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Catalog Number:
42196
CAS Number:
19542-67-7
BAIE 11-7082
Purity:
≥ 98 % (HPLC)
Synonym(s):
( E -3-tosylacrylonitrile, ( E -3-( p -Toluènesulfonyl)acrylonitrile
Documents
$46.77 /100 mg
Taille
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Informations sur le produit

BAY 11-7082 is a potent and selective inhibitor of the NF-κB signaling pathway, making it a valuable tool in both research and therapeutic applications. This compound has garnered attention for its ability to modulate inflammatory responses and has been utilized in studies exploring various diseases, including cancer and autoimmune disorders. Its unique sulfonylprop-2-enenitrile structure contributes to its efficacy in inhibiting the activation of NF-κB, which is crucial in regulating immune responses and cell survival. Researchers have found BAY 11-7082 particularly useful in in vitro and in vivo studies aimed at understanding the mechanisms of inflammation and tumorigenesis.

In addition to its applications in basic research, BAY 11-7082 holds promise in the development of novel therapeutic strategies. Its ability to selectively inhibit NF-κB provides a pathway for potential treatments that target inflammatory diseases and cancer. The compound's effectiveness in reducing cytokine production and promoting apoptosis in cancer cells highlights its relevance in the pharmaceutical industry. With its growing recognition, BAY 11-7082 is positioned as a significant compound for researchers and industry professionals seeking to explore innovative solutions in disease management.

Numéro CAS 
19542-67-7
Formule moléculaire
C 10 H 9 NO 2 S
Poids moléculaire 
207.25
Point de fusion 
132 - 136 °C
Informations générales
Numéro CAS 
19542-67-7
Formule moléculaire
C 10 H 9 NO 2 S
Poids moléculaire 
207.25
Point de fusion 
132 - 136 °C
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

BAY 11-7082 is widely utilized in research focused on:

  • Anti-inflammatory Research: This compound is known for its ability to inhibit NF-kB activation, making it valuable in studies aimed at understanding and treating inflammatory diseases.
  • Cancer Therapy Development: Researchers explore its potential in cancer treatment due to its role in inducing apoptosis in various cancer cell lines, providing a pathway for developing new therapeutic strategies.
  • Neuroscience Applications: It is used in neuroprotective studies, particularly in models of neurodegenerative diseases, helping to identify mechanisms that could lead to new treatments.
  • Cardiovascular Research: The compound's effects on cellular signaling pathways are studied to understand its implications in heart disease, potentially leading to novel cardiovascular therapies.
  • Drug Development: Its unique properties make it a candidate for formulating new drugs, especially those targeting inflammatory and autoimmune conditions, offering advantages over traditional treatments.

Citations