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Catalog Number:
12843
CAS Number:
211637-75-1
Fmoc-2-méthyl-L-phénylalanine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-L-Phe(2-Me)-OH, Fmoc- o -Me-L-Phe-OH, Fmoc-Phe(2-Me)-OH
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Informations sur le produit

Fmoc-2-methyl-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during solid-phase peptide synthesis (SPPS). Its unique structure not only enhances the stability of the peptide chains but also facilitates the introduction of aromatic side chains, making it an invaluable tool for researchers in the fields of medicinal chemistry and biochemistry.

The compound's ability to incorporate hydrophobic and sterically bulky side chains allows for the design of peptides with enhanced biological activity and specificity. Fmoc-2-methyl-L-phenylalanine has been effectively used in the synthesis of bioactive peptides, including those with potential therapeutic applications in cancer treatment and drug delivery systems. Its compatibility with various coupling reagents and solvents further supports its use in diverse synthetic strategies, making it a preferred choice for professionals aiming to develop innovative peptide-based therapeutics.

Numéro CAS 
211637-75-1
Formule moléculaire
C 25 H 234
Poids moléculaire 
401.46
Informations générales
Numéro CAS 
211637-75-1
Formule moléculaire
C 25 H 234
Poids moléculaire 
401.46
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-2-methyl-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, especially in solid-phase peptide synthesis, allowing for the creation of complex and functional peptides.
  • Drug Development: It plays a significant role in medicinal chemistry for developing new pharmaceuticals, particularly in designing peptide-based drugs that target specific biological pathways.
  • Biotechnology: Researchers use it in the production of therapeutic proteins, enhancing the efficacy and stability of biologics used in treatments.
  • Material Science: The chemical is applied in creating novel materials with specific properties, such as hydrophobicity or biocompatibility, which are crucial in various industrial applications.
  • Research and Development: It is frequently employed in academic and industrial labs for studying protein interactions and functions, providing insights into biochemical processes.

Citations