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Catalog Number:
07381
CAS Number:
205528-33-2
Fmoc-3-(4-thiazolyl)-D-alanine
Purity:
≥ 99 % (dosage par titrage sur base sèche)
Synonym(s):
Fmoc-D-Ala(4-thiazoyl)-OH, ( R - N -Fmoc-4-thiazoylalanine
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$106.96 /1G
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Informations sur le produit

Fmoc-3-(4-thiazolyl)-D-alanine is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino acids during the synthesis of peptides. Its unique thiazole side chain enhances the compound's bioactivity, making it particularly valuable in the design of bioactive peptides and pharmaceuticals. Researchers appreciate its stability and compatibility with various coupling reagents, facilitating efficient synthesis processes.

In practical applications, Fmoc-3-(4-thiazolyl)-D-alanine is employed in the development of peptide-based therapeutics, including antimicrobial agents and enzyme inhibitors. Its ability to introduce thiazole moieties into peptide sequences can lead to improved biological activity and specificity. This compound is also significant in the field of medicinal chemistry, where it aids in the exploration of new drug candidates. With its robust properties and diverse applications, Fmoc-3-(4-thiazolyl)-D-alanine stands out as a crucial tool for researchers and industry professionals aiming to innovate in peptide chemistry.

Numéro CAS 
205528-33-2
Formule moléculaire
C21H18N2O4S
Poids moléculaire 
394.45
Point de fusion 
178 - 182 °C
Rotation optique 
[a] 25 D = 13 ± 1,5 ° (C = 1 dans MeOH)
Informations générales
Numéro CAS 
205528-33-2
Formule moléculaire
C21H18N2O4S
Poids moléculaire 
394.45
Point de fusion 
178 - 182 °C
Rotation optique 
[a] 25 D = 13 ± 1,5 ° (C = 1 dans MeOH)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-3-(4-thiazolyl)-D-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective formation of peptide bonds while preventing unwanted reactions.
  • Drug Development: It plays a crucial role in the design of bioactive peptides, particularly in the pharmaceutical industry, where it aids in creating compounds with enhanced biological activity.
  • Bioconjugation: The chemical is used in bioconjugation processes, facilitating the attachment of peptides to various biomolecules, which is essential for developing targeted therapies.
  • Research in Neuroscience: Its derivatives are explored in studies related to neuropeptides, contributing to the understanding of neurological pathways and potential treatments for neurological disorders.
  • Antimicrobial Research: Fmoc-3-(4-thiazolyl)-D-alanine is investigated for its antimicrobial properties, making it valuable in the development of new antibiotics and treatments for resistant bacterial strains.

Citations