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Catalog Number:
30324
CAS Number:
1676104-73-6
Fmoc-Thr(tBu)-Thr[Psi (Me,Me) Pro]-OH
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-Thr(tBu)-Thr[Ψ(Me,Me)Pro]-OH, Acide (4S)-3-[N-(9-fluorénylméthyloxycarbonyl-O-tert-butyl-L-thréoninyl]-2,2,5-triméthyloxazolidine-4-carboxylique
Antibiotic
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$83.20 /1G
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Informations sur le produit

Fmoc-Thr(tBu)-Thr[Psi(Me,Me)Pro]-OH is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued in the field of medicinal chemistry for its ability to enhance the stability and bioavailability of peptides. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains while facilitating selective deprotection under mild conditions. Its unique structure, featuring a bulky tBu (tert-butyl) side chain and a Psi(Me,Me)Pro moiety, contributes to its effectiveness in stabilizing peptide conformations, making it an ideal choice for researchers focusing on the design of peptide-based therapeutics.

In practical applications, Fmoc-Thr(tBu)-Thr[Psi(Me,Me)Pro]-OH is utilized in the synthesis of cyclic peptides and peptidomimetics, which are essential in developing new drugs targeting various diseases. Its ability to improve solubility and reduce enzymatic degradation enhances the therapeutic potential of peptide drugs. Researchers and industry professionals can leverage this compound to create more effective and stable peptide formulations, ultimately leading to advancements in pharmaceutical development and therapeutic applications.

Numéro CAS 
1676104-73-6
Formule moléculaire
C30H38N2O7
Poids moléculaire 
538.64
Rotation optique 
[a] D 25 = 11 ± 2 º (C = 1 dans CH2Cl2)
Informations générales
Numéro CAS 
1676104-73-6
Formule moléculaire
C30H38N2O7
Poids moléculaire 
538.64
Rotation optique 
[a] D 25 = 11 ± 2 º (C = 1 dans CH2Cl2)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-Thr(tBu)-Thr[Psi(Me,Me)Pro] is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for drug development and biological studies.
  • Drug Development: Its unique properties enable the design of peptides with enhanced stability and bioactivity, making it valuable in pharmaceutical research for developing new therapeutics.
  • Bioconjugation: The compound can be used in bioconjugation processes, facilitating the attachment of peptides to other molecules, which is essential in creating targeted drug delivery systems.
  • Protein Engineering: Researchers leverage this chemical in protein engineering applications to modify protein structures, improving their functionality and interaction with other biomolecules.
  • Analytical Chemistry: It is also applied in analytical methods to study peptide interactions and stability, providing insights that are crucial for understanding biological processes.

Citations