N,N-Carbonyldiimidazole is widely utilized in research focused on:

• Peptide Synthesis: This compound serves as an effective coupling agent in the formation of peptide bonds, facilitating the synthesis of peptides in pharmaceutical research.
• Carbamate Formation: It is commonly used to convert alcohols into carbamates, which are important intermediates in the production of various agrochemicals and pharmaceuticals.
• Protein Modification: Researchers employ it for selective modification of amino acids in proteins, enhancing the study of protein function and interactions.
• Organic Synthesis: The compound acts as a versatile reagent in organic synthesis, particularly in the preparation of imidazole derivatives, which are valuable in medicinal chemistry.
• Bioconjugation: It is utilized in bioconjugation processes to link biomolecules, aiding in the development of targeted drug delivery systems and diagnostic tools.