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Catalog Number:
11638
CAS Number:
197632-77-2
Fmoc- N -méthyl- O - tert -butyl-L-sérine
Purity:
≥ 99,5 % (HPLC chirale)
Synonym(s):
Fmoc-N-Me-L-Ser(tBu)-OH
Documents
$68.50 /250 mg
Taille
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Informations sur le produit

Fmoc-N-methyl-O-tert-butyl-L-serine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it an essential building block for researchers in the field of medicinal chemistry. Its unique tert-butyl ether group enhances solubility and stability, facilitating its use in various organic reactions and applications.

Researchers and industry professionals appreciate Fmoc-N-methyl-O-tert-butyl-L-serine for its role in the synthesis of complex peptides and proteins, particularly in the development of therapeutic agents. Its ability to provide a stable and easily removable protecting group streamlines the synthesis process, allowing for greater efficiency and yield. Additionally, this compound is ideal for applications in combinatorial chemistry and high-throughput screening, where rapid and reliable synthesis is crucial. With its robust properties and practical applications, Fmoc-N-methyl-O-tert-butyl-L-serine stands out as a valuable asset in peptide chemistry.

Numéro CAS 
197632-77-2
Formule moléculaire
C 23 H 275
Poids moléculaire 
397.47
Rotation optique 
[a] D 20 = 2 ± 1 ° (C = 1 dans MeOH)
Informations générales
Numéro CAS 
197632-77-2
Formule moléculaire
C 23 H 275
Poids moléculaire 
397.47
Rotation optique 
[a] D 20 = 2 ± 1 ° (C = 1 dans MeOH)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-N-methyl-O-tert-butyl-L-serine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It plays a crucial role in the development of peptide-based therapeutics, particularly in designing drugs that target specific biological pathways.
  • Bioconjugation: The chemical is used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.
  • Research in Protein Engineering: Researchers leverage this compound to modify serine residues in proteins, enhancing their stability and activity for various applications in biotechnology.
  • Analytical Chemistry: It is employed in analytical techniques to study protein interactions and dynamics, providing insights into molecular behavior in complex biological systems.

Citations