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Catalog Number:
05743
CAS Number:
152548-66-8
Fmoc-N-Me-Asp(OtBu)-OH
Purity:
≥ 98 % (HPLC)
Synonym(s):
Ester β-tert-butylique de l'acide Fmoc-N-méthyl-L-aspartique
Documents
$86.23 /250 mg
Taille
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Product Information

Fmoc-N-methyl-Asp(OtBu)-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during solid-phase peptide synthesis. Its unique structure, characterized by the presence of a methyl group and a t-butyl ester, enhances its stability and solubility, making it an ideal choice for researchers looking to streamline their synthesis processes.

In practical applications, Fmoc-N-methyl-Asp(OtBu)-OH is particularly valuable in the development of peptide-based therapeutics and in the study of protein interactions. Its ability to facilitate the synthesis of complex peptides allows for the exploration of novel drug candidates and biomolecules. Researchers in pharmaceutical and biotechnological fields will find this compound beneficial for its efficiency in producing high-purity peptides, ultimately accelerating the drug discovery process.

Synonyms
Ester β-tert-butylique de l'acide Fmoc-N-méthyl-L-aspartique
CAS Number
152548-66-8
Purity
≥ 98 % (HPLC)
Molecular Formula
C 24 H 276
Molecular Weight
425.5
MDL Number
MFCD00237027
PubChem ID
44181934
Appearance
Solide blanc à blanc cassé
Optical Rotation
[a] D 20 = -38 ± 1 º (C = 1 dans DMF) D 20 = -11 ± 2º (C = 1 dans MeOH)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Ester β-tert-butylique de l'acide Fmoc-N-méthyl-L-aspartique
CAS Number
152548-66-8
Purity
≥ 98 % (HPLC)
Molecular Formula
C 24 H 276
Molecular Weight
425.5
MDL Number
MFCD00237027
PubChem ID
44181934
Appearance
Solide blanc à blanc cassé
Optical Rotation
[a] D 20 = -38 ± 1 º (C = 1 dans DMF) D 20 = -11 ± 2º (C = 1 dans MeOH)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-N-methyl-Asp(OtBu)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity and yield.
  • Drug Development: It plays a crucial role in the development of peptide-based therapeutics, offering a way to modify peptide structures for enhanced stability and bioactivity, which is essential in pharmaceutical research.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach peptides to various biomolecules, facilitating the design of targeted drug delivery systems and diagnostic agents.
  • Research in Neuroscience: Due to its structural properties, it is employed in studies related to neurotransmitter analogs, aiding researchers in understanding synaptic functions and developing potential treatments for neurological disorders.
  • Protein Engineering: This compound is beneficial in protein engineering applications, allowing scientists to introduce specific modifications to proteins, which can enhance their function or stability in various industrial and research settings.

Citations