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Catalog Number:
02682
CAS Number:
103478-58-6
Fmoc- N -méthyl-D-valine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc- N -Me-D-Val-OH
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Informations sur le produit

Fmoc-N-methyl-D-valine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for efficient incorporation into peptides, enhancing stability and facilitating purification processes. Researchers and industry professionals appreciate its role in the development of pharmaceuticals, particularly in the design of peptide-based therapeutics and biologically active compounds.

In addition to its applications in peptide synthesis, Fmoc-N-methyl-D-valine is also valuable in the study of protein interactions and structure-function relationships. Its ability to mimic natural amino acids while providing additional functional groups makes it an excellent choice for creating modified peptides with enhanced properties. This compound stands out for its ease of use and compatibility with various coupling reagents, making it a preferred choice for chemists looking to streamline their synthesis processes.

Numéro CAS 
103478-58-6
Formule moléculaire
C 21 H 234
Poids moléculaire 
353.4
Rotation optique 
[a] 20 D = 66 - 70 ° (C=1 dans DMF)
Informations générales
Numéro CAS 
103478-58-6
Formule moléculaire
C 21 H 234
Poids moléculaire 
353.4
Rotation optique 
[a] 20 D = 66 - 70 ° (C=1 dans DMF)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-N-methyl-D-valine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing peptide-based drugs, which can be more effective and have fewer side effects compared to traditional small-molecule drugs.
  • Bioconjugation: The chemical is used in bioconjugation techniques, enabling researchers to attach biomolecules to peptides, enhancing their functionality for targeted drug delivery systems.
  • Protein Engineering: In the field of protein engineering, it aids in modifying protein structures, improving their stability and activity, which is crucial for therapeutic applications.
  • Research in Neuroscience: Fmoc-N-methyl-D-valine is utilized in studies related to neuropeptides, contributing to the understanding of neurological functions and potential treatments for neurodegenerative diseases.

Citations