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Catalog Number:
08078
CAS Number:
252049-06-2
Fmoc- N -méthyl-L-thréonine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc- N -Me-L-Thr-OH
Documents
$72.31 /100 mg
Taille
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Informations sur le produit

Fmoc-N-methyl-L-threonine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique structure not only enhances stability but also facilitates the efficient coupling of amino acids, making it an essential building block in the production of complex peptides and proteins. Researchers and industry professionals appreciate its role in developing therapeutic peptides, particularly in the fields of pharmaceuticals and biotechnology, where precision and efficiency are paramount.

The compound's N-methyl substitution offers improved solubility and reactivity, which can lead to higher yields in peptide synthesis compared to traditional amino acids. Fmoc-N-methyl-L-threonine is particularly beneficial in the synthesis of cyclic peptides and peptidomimetics, where the incorporation of non-natural amino acids can significantly enhance biological activity and stability. Its application extends to the development of novel drug candidates, providing researchers with a powerful tool for advancing therapeutic innovations.

Numéro CAS 
252049-06-2
Formule moléculaire
C 20 H 215
Poids moléculaire 
355.39
Point de fusion 
152 - 157 ?C
Informations générales
Numéro CAS 
252049-06-2
Formule moléculaire
C 20 H 215
Poids moléculaire 
355.39
Point de fusion 
152 - 157 ?C
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-N-methyl-L-threonine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures with high purity.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for developing peptide-based drugs, enhancing the efficacy and specificity of therapeutic agents.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps in attaching biomolecules to drugs or imaging agents, improving delivery and targeting in medical applications.
  • Research in Protein Engineering: Researchers utilize it to modify proteins, enabling the study of protein interactions and functions, which is essential in understanding biological processes.
  • Development of Diagnostic Tools: It aids in creating diagnostic assays by incorporating into biosensors, enhancing sensitivity and specificity for detecting various diseases.

Citations