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Catalog Number:
02572
CAS Number:
1132-68-9
4-Fluoro-L-phénylalanine
Purity:
≥ 99 % (HPLC, HPLC chirale)
Synonym(s):
L-Phe(4-F)-OH, p -Fluoro-L-phénylalanine, ( Acide S -2-amino-3-(4-fluorophényl)propionique
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$18.53 /1G
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Informations sur le produit

4-Fluoro-L-phenylalanine is a valuable amino acid derivative that has garnered attention in pharmaceutical and biochemical research. This compound is recognized for its unique fluorinated structure, which enhances its utility in various applications, particularly in the development of novel therapeutics. Researchers utilize 4-Fluoro-L-phenylalanine in the synthesis of peptide-based drugs, where the fluorine atom can influence the biological activity and stability of the resulting compounds. Its incorporation into peptides can lead to improved binding affinities and altered pharmacokinetic properties, making it a crucial building block in drug design.

In addition to its role in medicinal chemistry, 4-Fluoro-L-phenylalanine is also employed in studies related to protein engineering and enzyme activity modulation. By substituting standard amino acids with this fluorinated variant, scientists can investigate the effects of fluorination on protein structure and function. This compound's ability to enhance the selectivity and efficacy of therapeutic agents positions it as a key player in advancing drug discovery and development processes.

Numéro CAS 
1132-68-9
Formule moléculaire
C9H10FNO2
Poids moléculaire 
183.2
Point de fusion 
211-213 °C (déc.)
Informations générales
Numéro CAS 
1132-68-9
Formule moléculaire
C9H10FNO2
Poids moléculaire 
183.2
Point de fusion 
211-213 °C (déc.)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

4-Fluoro-L-phenylalanine is widely utilized in research focused on:

  • Drug Development: This compound serves as a building block in the synthesis of novel pharmaceuticals, particularly in the design of drugs targeting neurological disorders.
  • Protein Engineering: It is used to introduce fluorine into proteins, which can enhance their stability and activity, making it valuable in biochemistry and molecular biology.
  • Radiolabeling: The fluorine atom allows for the incorporation of this amino acid into radiolabeled compounds, facilitating imaging techniques in medical diagnostics.
  • Research on Neurotransmitters: It aids in studying the role of phenylalanine derivatives in neurotransmitter function, contributing to neuroscience research.
  • Anticancer Research: The compound has potential applications in developing anticancer agents, as modifications in amino acids can lead to improved therapeutic efficacy.

Citations