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Catalog Number:
30526
CAS Number:
684270-46-0
Solvate d'acide N α -Fmoc-N β -Azido-L-2,3-diaminopropionique avec DIPE
Purity:
≥ 94 % (dosage par titration)
Synonym(s):
Acide 2-( S )-Fmoc-amino-3-azidopropanoïque, Fmoc-L-Dap(N3)-OH
Documents
$120.88 /250 mg
Taille
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Informations sur le produit

Na-Fmoc-Nb-Azido-L-2,3-diaminopropionic acid is a versatile compound widely utilized in peptide synthesis and medicinal chemistry. This amino acid derivative, featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group and an azido functional group, serves as a crucial building block in the development of bioactive peptides and pharmaceuticals. Its unique structure allows for selective reactions, making it an ideal candidate for applications in drug discovery and development. Researchers appreciate its stability under various conditions and its compatibility with standard coupling reagents, facilitating efficient synthesis processes.

In addition to its role in peptide synthesis, Na-Fmoc-Nb-Azido-L-2,3-diaminopropionic acid is also employed in click chemistry, enabling the formation of diverse molecular architectures. This compound's azido group can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC), a powerful tool for bioconjugation and labeling studies. Its ability to enhance the solubility and bioavailability of peptides further underscores its significance in pharmaceutical formulations. Overall, this compound stands out for its practical applications in research and industry, offering significant advantages in the synthesis of complex biomolecules.

Numéro CAS 
684270-46-0
Formule moléculaire
C18H16N4O4
Poids moléculaire 
352.3
Point de fusion 
117 - 130 °C
Rotation optique 
[a] D 20 = -8 à -11 º (C=1 dans DMF)
Informations générales
Numéro CAS 
684270-46-0
Formule moléculaire
C18H16N4O4
Poids moléculaire 
352.3
Point de fusion 
117 - 130 °C
Rotation optique 
[a] D 20 = -8 à -11 º (C=1 dans DMF)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Na-Fmoc-Nb-Azido-L-2,3-diaminopropionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for drug development.
  • Bioconjugation: Its azido group enables selective labeling and conjugation with biomolecules, facilitating studies in targeted drug delivery and imaging.
  • Protein Engineering: Used in the modification of proteins, it helps in creating novel protein variants with enhanced properties for therapeutic applications.
  • Research in Neuroscience: The compound can be utilized to study neuropeptides, contributing to advancements in understanding neurological disorders.
  • Material Science: It can be incorporated into polymer matrices for developing smart materials with specific functionalities, such as drug release systems.

Citations