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Catalog Number:
05697
CAS Number:
109745-15-5
Ester butylique d'acide Fmoc-D-glutamique-a- tert
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-D-Glu-OtBu
Documents
$55.40 /250 mg
Taille
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Informations sur le produit

Fmoc-D-glutamic acid-a-tert-butyl ester is a versatile compound widely utilized in peptide synthesis and drug development. This protected amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) group, which provides stability and ease of handling during the synthesis process. Its unique tert-butyl ester group enhances solubility and reactivity, making it an ideal choice for researchers focused on the development of complex peptides and proteins. The compound's structure allows for selective deprotection, facilitating the incorporation of D-glutamic acid into peptide chains, which is crucial for various applications in medicinal chemistry and biochemistry.

In addition to its role in peptide synthesis, Fmoc-D-glutamic acid-a-tert-butyl ester is also valuable in the production of pharmaceuticals and biologically active compounds. Its ability to serve as a building block for more complex molecules opens up possibilities in drug design, particularly in the development of therapeutics targeting neurological disorders, where glutamic acid plays a significant role. Researchers and industry professionals will find this compound beneficial for its efficiency and effectiveness in producing high-purity peptides, ultimately advancing their projects in drug discovery and development.

Numéro CAS 
109745-15-5
Formule moléculaire
C 24 H 276
Poids moléculaire 
425.5
Point de fusion 
104 - 111 °C
Rotation optique 
[a]D20 = 10,5 ± 1 ° (C=1 dans AcOH)
Informations générales
Numéro CAS 
109745-15-5
Formule moléculaire
C 24 H 276
Poids moléculaire 
425.5
Point de fusion 
104 - 111 °C
Rotation optique 
[a]D20 = 10,5 ± 1 ° (C=1 dans AcOH)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
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Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-D-glutamic acid-a-tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures with specific functionalities.
  • Drug Development: It plays a crucial role in the pharmaceutical industry, particularly in designing and optimizing drug candidates that target glutamate receptors, which are involved in various neurological conditions.
  • Bioconjugation: The compound is used in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, enhancing the efficacy of therapeutic agents.
  • Research in Neuroscience: It aids in studying neurotransmitter systems, particularly in understanding the role of glutamate in synaptic transmission and plasticity.
  • Custom Synthesis: Researchers benefit from its versatility in custom synthesis projects, allowing for the modification of amino acids to tailor specific properties for various applications.

Citations