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Catalog Number:
01376
CAS Number:
37784-17-1
Boc-D-proline
Purity:
≥ 99,5 % (HPLC chirale)
Synonym(s):
Boc-D-Pro-OH, Acide ( R )-Boc-pyrrolidine-2-carboxylique
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Informations sur le produit

Boc-D-proline is a valuable amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a tert-butoxycarbonyl (Boc) protecting group, which enhances its stability and solubility, making it an ideal choice for various applications in organic synthesis. Researchers often employ Boc-D-proline in the development of bioactive peptides and as a building block in the synthesis of complex molecules. Its unique structure allows for the introduction of proline residues into peptides, which can significantly influence the conformation and biological activity of the resulting compounds.

In addition to its role in peptide synthesis, Boc-D-proline is also used in the design of inhibitors and modulators for various biological targets, including enzymes and receptors. Its ability to mimic natural amino acids while providing enhanced stability makes it a preferred choice for medicinal chemists and biochemists. With its versatile applications and essential role in the development of therapeutic agents, Boc-D-proline stands out as a crucial compound for researchers aiming to innovate in drug discovery and development.

Numéro CAS 
37784-17-1
Formule moléculaire
C 10 H 17 NON 4
Poids moléculaire 
215.3
Point de fusion 
130 - 138 °C
Rotation optique 
[a] D 20 = 60 ± 2 º (C = 1 dans AcOH)
Informations générales
Numéro CAS 
37784-17-1
Formule moléculaire
C 10 H 17 NON 4
Poids moléculaire 
215.3
Point de fusion 
130 - 138 °C
Rotation optique 
[a] D 20 = 60 ± 2 º (C = 1 dans AcOH)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
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Réglementé par la DEA
Non
Avertissements 
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Applications

Boc-D-proline is widely utilized in research focused on:

  • Peptide Synthesis: It serves as a key building block in the synthesis of peptides, particularly in the development of pharmaceuticals and biologically active compounds.
  • Drug Development: Researchers leverage Boc-D-proline for its ability to enhance the stability and bioavailability of drug candidates, making it a valuable component in medicinal chemistry.
  • Protein Engineering: This compound is used to modify proteins, allowing scientists to study protein folding and interactions, which is crucial for understanding diseases.
  • Chiral Resolution: Boc-D-proline is effective in separating enantiomers in chiral synthesis, aiding in the production of optically pure compounds for various applications.
  • Material Science: Its unique properties are exploited in creating novel materials, such as hydrogels, which have applications in drug delivery and tissue engineering.

Citations