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Catalog Number:
03784
CAS Number:
2419-94-5
Acide Boc-L-glutamique
Purity:
≥ 98 % (HPLC)
Synonym(s):
Boc-L-Glu-OH
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Product Information

Boc-L-glutamic acid is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound, known for its protective Boc (tert-butyloxycarbonyl) group, enhances the stability and solubility of peptides during synthesis, making it an essential building block in the development of bioactive compounds. Its unique structure allows for selective deprotection, facilitating the formation of complex peptides that are crucial in drug development and therapeutic applications. Researchers appreciate its role in creating peptide-based drugs, particularly in the fields of oncology and immunology, where precise molecular design is paramount.

In addition to its applications in peptide synthesis, Boc-L-glutamic acid serves as a valuable reagent in organic synthesis and can be employed in the preparation of various derivatives. Its compatibility with different coupling agents and reagents makes it a preferred choice for chemists aiming to streamline their synthetic pathways. The compound's ability to enhance the efficiency of peptide coupling reactions while maintaining high yields underscores its significance in both academic and industrial settings.

Synonyms
Boc-L-Glu-OH
CAS Number
2419-94-5
Purity
≥ 98 % (HPLC)
Molecular Formula
C 10 H 176
Molecular Weight
247.25
MDL Number
MFCD00037297
PubChem ID
433622
Melting Point
110-116 °C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -14 ± 2º (C=1 dans MeOH)
Conditions
Conserver à 0-8°C
General Information
Synonyms
Boc-L-Glu-OH
CAS Number
2419-94-5
Purity
≥ 98 % (HPLC)
Molecular Formula
C 10 H 176
Molecular Weight
247.25
MDL Number
MFCD00037297
PubChem ID
433622
Melting Point
110-116 °C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -14 ± 2º (C=1 dans MeOH)
Conditions
Conserver à 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Boc-L-glutamic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group for amino acids during peptide synthesis, allowing for the selective modification of other functional groups without interference.
  • Drug Development: It plays a crucial role in the design of pharmaceuticals, particularly in the development of prodrugs that enhance bioavailability and reduce side effects.
  • Bioconjugation: Researchers use Boc-L-glutamic acid to create bioconjugates, which are essential in targeted drug delivery systems, improving the efficacy of therapeutic agents.
  • Protein Engineering: It is applied in the modification of proteins to study structure-function relationships, aiding in the development of novel enzymes and therapeutic proteins.
  • Diagnostic Applications: The compound is also used in the synthesis of diagnostic agents, enhancing imaging techniques in medical research and clinical diagnostics.

Citations