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Catalog Number:
05680
CAS Number:
86060-83-5
Ester α-benzylique de l'acide Fmoc-L-aspartique
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-L-Asp-OBzl
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Product Information

Fmoc-L-aspartic acid a-benzyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure not only enhances stability but also facilitates the formation of complex peptides, making it a preferred choice for researchers in the field of medicinal chemistry and biochemistry.

The compound's benzyl ester functionality further contributes to its utility, allowing for easy cleavage under mild conditions, which is advantageous in various synthetic pathways. Fmoc-L-aspartic acid a-benzyl ester is particularly relevant in the development of peptide-based therapeutics, where precise control over amino acid sequences is crucial. Its application extends to the synthesis of bioactive peptides, drug delivery systems, and in the study of protein interactions, showcasing its importance in advancing research and innovation in the pharmaceutical industry.

Synonyms
Fmoc-L-Asp-OBzl
CAS Number
86060-83-5
Purity
≥ 99 % (HPLC)
Molecular Formula
C 26 H 236
Molecular Weight
445.48
MDL Number
MFCD00198201
PubChem ID
15601631
Appearance
Poudre ou solide blanc à blanc cassé
Optical Rotation
[a]20D = -21 ± 1 ° (C=1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-Asp-OBzl
CAS Number
86060-83-5
Purity
≥ 99 % (HPLC)
Molecular Formula
C 26 H 236
Molecular Weight
445.48
MDL Number
MFCD00198201
PubChem ID
15601631
Appearance
Poudre ou solide blanc à blanc cassé
Optical Rotation
[a]20D = -21 ± 1 ° (C=1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-L-aspartic acid a-benzyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It plays a crucial role in the development of pharmaceutical compounds, particularly in creating drug candidates that require specific amino acid sequences for efficacy.
  • Bioconjugation: The compound is used in bioconjugation techniques, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted therapies.
  • Research in Neuroscience: It aids in the study of neurotransmitter pathways by allowing researchers to create analogs of aspartic acid, which is important for understanding brain function and disorders.
  • Material Science: The compound is also explored in the development of novel materials, such as hydrogels, which can be used in drug delivery systems and tissue engineering.

Citations