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Catalog Number:
03907
CAS Number:
200335-40-6
α-amide de l'acide Fmoc-L-aspartique
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-L-Asp-NH2, Fmoc-L- iso -asparagine
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Product Information

Fmoc-L-aspartic acid a-amide is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which facilitates the selective protection of the amino group during the synthesis of peptides. Its unique structure allows for the efficient incorporation of aspartic acid into peptides, making it an essential building block in the development of bioactive compounds and pharmaceuticals. Researchers appreciate its stability and compatibility with various coupling reagents, which enhances its utility in solid-phase peptide synthesis (SPPS).

In addition to its role in peptide synthesis, Fmoc-L-aspartic acid a-amide is also employed in the design of peptide-based therapeutics and in the study of protein interactions. Its ability to form stable peptide bonds makes it a valuable tool for creating complex peptide sequences that can mimic natural proteins. The compound's favorable properties, such as solubility and reactivity, position it as a preferred choice for researchers looking to explore new therapeutic avenues or develop innovative biomaterials.

Synonyms
Fmoc-L-Asp-NH2, Fmoc-L- iso -asparagine
CAS Number
200335-40-6
Purity
≥ 99 % (HPLC)
Molecular Formula
C19H18N2O5
Molecular Weight
354.36
MDL Number
MFCD00151920
PubChem ID
4122815
Melting Point
185-190 °C
Appearance
Poudre cristalline blanche
Optical Rotation
[α] D 20 = -18,0 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8°C
General Information
Synonyms
Fmoc-L-Asp-NH2, Fmoc-L- iso -asparagine
CAS Number
200335-40-6
Purity
≥ 99 % (HPLC)
Molecular Formula
C19H18N2O5
Molecular Weight
354.36
MDL Number
MFCD00151920
PubChem ID
4122815
Melting Point
185-190 °C
Appearance
Poudre cristalline blanche
Optical Rotation
[α] D 20 = -18,0 ± 2º (C = 1 dans DMF)
Conditions
Conserver à 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-L-aspartic acid a-amide is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex molecules for various applications in drug development.
  • Drug Design: Its structural properties enable the design of novel pharmaceuticals, particularly in targeting neurological disorders where aspartic acid plays a crucial role.
  • Bioconjugation: Fmoc-L-aspartic acid a-amide can be used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other compounds, enhancing drug delivery systems.
  • Research in Neuroscience: The compound is instrumental in studying neurotransmitter functions, as aspartic acid is a vital neurotransmitter in the brain, helping researchers understand various neurological conditions.
  • Protein Engineering: It is also applied in protein engineering to modify proteins for improved stability and functionality, which is essential in developing new biotechnological applications.

Citations