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Catalog Number:
02395
CAS Number:
129460-09-9
Acide Fmoc-L-aspartique-α- tert -butylester
Purity:
≥ 99,5 % (HPLC chirale)
Synonym(s):
Fmoc-L-Asp-OtBu
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Product Information

Fmoc-L-aspartic acid-a-tert-butylester is a versatile compound widely utilized in peptide synthesis and organic chemistry. This derivative of aspartic acid features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino acids during solid-phase peptide synthesis. Its tert-butyl ester group enhances solubility and stability, making it an ideal choice for researchers and professionals engaged in the development of peptides and proteins. The compound's unique structure allows for efficient coupling reactions, facilitating the synthesis of complex peptides with high purity and yield.

In addition to its role in peptide synthesis, Fmoc-L-aspartic acid-a-tert-butylester is also employed in various applications within pharmaceutical research and development. Its ability to protect functional groups while maintaining reactivity makes it a valuable tool for chemists working on drug design and development. Researchers appreciate its compatibility with a range of coupling reagents, which streamlines the synthesis process and enhances overall productivity. With its robust performance and reliability, this compound is an essential asset for laboratories focused on peptide chemistry and related fields.

Synonyms
Fmoc-L-Asp-OtBu
CAS Number
129460-09-9
Purity
≥ 99,5 % (HPLC chirale)
Molecular Formula
C 23 H 256
Molecular Weight
411.5
MDL Number
MFCD00065631
Melting Point
100 - 118 °C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -23 ± 2,5 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-Asp-OtBu
CAS Number
129460-09-9
Purity
≥ 99,5 % (HPLC chirale)
Molecular Formula
C 23 H 256
Molecular Weight
411.5
MDL Number
MFCD00065631
Melting Point
100 - 118 °C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = -23 ± 2,5 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-L-aspartic acid-a-tert-butylester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the efficient assembly of complex peptide structures.
  • Drug Development: It plays a crucial role in the development of pharmaceutical compounds, especially in creating peptide-based drugs that target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The chemical is used in bioconjugation processes, linking biomolecules to improve drug delivery systems, which can enhance the stability and bioavailability of therapeutic agents.
  • Research in Neuroscience: It is utilized in studies related to neurotransmitter pathways, particularly in the synthesis of aspartate derivatives that can help in understanding neurological functions and disorders.
  • Protein Engineering: This compound aids in the modification of proteins, allowing researchers to tailor protein properties for specific applications in biotechnology and medicine, providing advantages in stability and activity compared to unmodified proteins.

Citations