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Catalog Number:
02392
CAS Number:
86060-84-6
Ester β-benzylique de l'acide Fmoc-L-aspartique
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-L-Asp(OBzl)-OH
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Product Information

Fmoc-L-aspartic acid b-benzyl ester is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for the efficient coupling of aspartic acid in solid-phase peptide synthesis, making it an invaluable tool for researchers in the fields of biochemistry and pharmaceutical development. The b-benzyl ester enhances the compound's stability and solubility, facilitating its use in various organic reactions and increasing its compatibility with different solvents.

This compound is particularly beneficial in the synthesis of bioactive peptides and proteins, which are crucial for therapeutic applications. Its ability to provide a stable and easily removable protecting group allows for the streamlined production of complex peptide sequences. Researchers appreciate its high purity and reliability, which contribute to reproducible results in experimental settings. Fmoc-L-aspartic acid b-benzyl ester stands out among similar compounds due to its favorable properties, making it a preferred choice for professionals aiming to advance their work in peptide chemistry.

Synonyms
Fmoc-L-Asp(OBzl)-OH
CAS Number
86060-84-6
Purity
≥ 98 % (HPLC)
Molecular Formula
C 26 H 236
Molecular Weight
445.5
MDL Number
MFCD00065630
Melting Point
122 - 126 °C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = - 20 ± 2 º (C = 1 dans DMF) D 20 = 1 ± 2 º (C = 1 dans MeOH)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-Asp(OBzl)-OH
CAS Number
86060-84-6
Purity
≥ 98 % (HPLC)
Molecular Formula
C 26 H 236
Molecular Weight
445.5
MDL Number
MFCD00065630
Melting Point
122 - 126 °C
Appearance
Poudre blanche
Optical Rotation
[a] D 20 = - 20 ± 2 º (C = 1 dans DMF) D 20 = 1 ± 2 º (C = 1 dans MeOH)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Fmoc-L-aspartic acid b-benzyl ester is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: It plays a crucial role in medicinal chemistry, where it is used to develop peptide-based drugs, enhancing bioactivity and specificity in therapeutic applications.
  • Bioconjugation: The compound is valuable in bioconjugation processes, enabling the attachment of biomolecules to drugs or imaging agents, thus improving targeting and efficacy in drug delivery systems.
  • Research in Neuroscience: It is utilized in studies related to neurotransmitter pathways, particularly in the synthesis of aspartate derivatives that can help in understanding neurological functions.
  • Custom Chemical Synthesis: Researchers leverage its properties for custom synthesis projects, providing a versatile option for creating tailored compounds in various chemical research applications.

Citations