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Catalog Number:
29632
CAS Number:
1185841-84-2
N a -Fmoc- N w , N w -diméthyl- N w' -(2,2,4,6,7-pentaméthyldihydrobenzofuran-5-sulfonyl)-L-arginine
Purity:
≥ 96 % (HPLC)
Synonym(s):
Fmoc-L-ADMA(Pbf)-OH
Documents
$100.00 /25 mg
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Product Information

Na-Fmoc-Nw, Nw-dimethyl-Nw'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine is a specialized amino acid derivative that plays a significant role in peptide synthesis and drug development. This compound is particularly valued for its unique sulfonyl group, which enhances the stability and solubility of peptides, making it an ideal choice for researchers focused on developing therapeutic peptides. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into solid-phase peptide synthesis, facilitating the creation of complex peptide structures with high purity and yield.

The compound's distinctive structure, featuring a pentamethyl-dihydrobenzofuran moiety, provides additional hydrophobic characteristics that can improve the pharmacokinetic properties of peptides. This makes it particularly useful in pharmaceutical applications where enhanced bioavailability is desired. Researchers in medicinal chemistry and biochemistry will find Na-Fmoc-Nw, Nw-dimethyl-Nw'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine to be a valuable tool in their quest for innovative drug solutions.

Synonyms
Fmoc-L-ADMA(Pbf)-OH
CAS Number
1185841-84-2
Purity
≥ 96 % (HPLC)
Molecular Formula
C 36 H 44 N 4 O 7 S
Molecular Weight
676.83
MDL Number
MFCD15141977
PubChem ID
138111743
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = -8 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
General Information
Synonyms
Fmoc-L-ADMA(Pbf)-OH
CAS Number
1185841-84-2
Purity
≥ 96 % (HPLC)
Molecular Formula
C 36 H 44 N 4 O 7 S
Molecular Weight
676.83
MDL Number
MFCD15141977
PubChem ID
138111743
Appearance
Poudre blanche à blanc cassé
Optical Rotation
[a] D 20 = -8 ± 2 º (C = 1 dans DMF)
Conditions
Conserver à 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

Na-Fmoc-Nw, Nw-dimethyl-Nw'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions and facilitating the construction of complex peptide chains.
  • Drug Development: It plays a crucial role in the development of peptide-based therapeutics, particularly in designing drugs that target specific biological pathways.
  • Bioconjugation: Researchers use it to create bioconjugates, which are essential for developing targeted drug delivery systems and improving the efficacy of therapeutic agents.
  • Protein Engineering: The compound is valuable in modifying proteins to enhance their stability and activity, which is critical in various biotechnological applications.
  • Diagnostic Tools: It is also applied in the development of diagnostic assays, helping to create sensitive detection methods for various diseases.

Citations