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Catalog Number:
02371
CAS Number:
73724-40-0
Ester N -hydroxysuccinimide de Fmoc-L-alanine
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-L-Ala-OSu
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Informations sur le produit

Fmoc-L-alanine N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and drug development. This compound serves as a protective group for amino acids, particularly in the formation of peptide bonds, allowing for the selective modification of peptides without interfering with other functional groups. Its unique structure not only enhances the stability of the amino acid during synthesis but also facilitates the efficient coupling of amino acids in solid-phase peptide synthesis (SPPS). Researchers appreciate its ability to streamline the synthesis process, leading to higher yields and purities in the final peptide products.

In addition to its role in peptide synthesis, Fmoc-L-alanine N-hydroxysuccinimide ester is also valuable in the development of bioconjugates and drug delivery systems. Its reactivity with various nucleophiles allows for the creation of targeted delivery mechanisms, making it an essential tool in pharmaceutical research. The compound's compatibility with a range of solvents and reaction conditions further enhances its applicability in diverse chemical environments, making it a preferred choice for professionals in the fields of biochemistry and medicinal chemistry.

Numéro CAS 
73724-40-0
Formule moléculaire
C22H20N2O6
Poids moléculaire 
408.4
Point de fusion 
158-164 ºC
Rotation optique 
[a] D 20 = -33 ± 2º (C = 1 dans THF)
Informations générales
Numéro CAS 
73724-40-0
Formule moléculaire
C22H20N2O6
Poids moléculaire 
408.4
Point de fusion 
158-164 ºC
Rotation optique 
[a] D 20 = -33 ± 2º (C = 1 dans THF)
Propriétés
Informations complémentaires sur la propriété à venir prochainement !
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Sécurité et réglementation
Matières dangereuses
-
Antibiotique
-
Réglementé par la DEA
Non
Avertissements 
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Applications

Fmoc-L-alanine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, enabling the efficient assembly of peptides for various applications in biochemistry and pharmaceuticals.
  • Drug Development: It is used in the development of peptide-based drugs, providing a stable and effective means to modify peptide structures for enhanced therapeutic properties.
  • Bioconjugation: The N-hydroxysuccinimide group allows for selective coupling with amines, making it ideal for bioconjugation processes in creating targeted drug delivery systems.
  • Protein Engineering: Researchers utilize this compound to modify proteins, enhancing their stability and functionality, which is crucial in the development of new biotherapeutics.
  • Diagnostics: It plays a role in the creation of diagnostic tools, such as biosensors, by facilitating the attachment of biomolecules to surfaces for improved detection capabilities.

Citations