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Catalog Number:
48072
CAS Number:
40733-27-5
3'- O- [ tert -butyl(diméthyl)silyl]thymidine
Purity:
≥ 98 % (HPLC)
Synonym(s):
3'- O- (TBDMS)Thymidine
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$143.00 /250 mg
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Product Information

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Synonyms
3'- O- (TBDMS)Thymidine
CAS Number
40733-27-5
Purity
≥ 98 % (HPLC)
Molecular Formula
C16H28N2O5Si
Molecular Weight
356.49
MDL Number
MFCD01631040
Appearance
Poudre blanche à jaune clair
Optical Rotation
[a]D20 = 26 - 30 ° (C=1 dans le chloroforme)
Conditions
Conserver entre 2 et 8 °C
General Information
Synonyms
3'- O- (TBDMS)Thymidine
CAS Number
40733-27-5
Purity
≥ 98 % (HPLC)
Molecular Formula
C16H28N2O5Si
Molecular Weight
356.49
MDL Number
MFCD01631040
Appearance
Poudre blanche à jaune clair
Optical Rotation
[a]D20 = 26 - 30 ° (C=1 dans le chloroforme)
Conditions
Conserver entre 2 et 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Non
Antibiotic
Non
DEA-regulated
Non
Warnings
-
Applications

3'-O-[tert-Butyl(dimethyl)silyl]thymidine is widely utilized in research focused on:

  • Nucleoside Synthesis: This compound serves as a key intermediate in the synthesis of modified nucleosides, which are crucial for developing antiviral and anticancer therapies.
  • Drug Development: It is used in the creation of prodrugs that enhance the bioavailability of nucleoside analogs, improving their therapeutic efficacy in clinical applications.
  • Biochemical Research: Researchers employ this compound to study DNA and RNA interactions, aiding in the understanding of genetic processes and the development of gene therapies.
  • Analytical Chemistry: It is utilized as a standard in chromatographic techniques, helping to quantify nucleoside derivatives in complex biological samples.
  • Material Science: The compound is explored in the development of novel materials for drug delivery systems, enhancing the targeted delivery of therapeutic agents.

Citations